Self-Healing Supramolecular Hydrogels for Tissue Engineering Applications

被引：205

作者：

Saunders, Laura ^{[1
]}

Ma, Peter X. ^{[1
,2
,3
,4
]}

机构：

[1] Univ Michigan, Macromol Sci & Engn Ctr, Ann Arbor, MI 48109 USA

[2] Univ Michigan, Biol & Mat Sci, Ann Arbor, MI 48109 USA

[3] Univ Michigan, Biomed Engn, Ann Arbor, MI 48109 USA

[4] Univ Michigan, Mat Sci & Engn, Ann Arbor, MI 48109 USA

来源：

MACROMOLECULAR BIOSCIENCE | 2019年 / 19卷 / 01期

基金：

美国国家卫生研究院;

关键词：

biomaterials; hydrogels; self-healing; supramolecular; tissue engineering; CYCLODEXTRIN INCLUSION COMPLEX; ASSEMBLING PEPTIDE HYDROGEL; LINKED ALGINATE HYDROGELS; DOUBLE-NETWORK HYDROGELS; SHAPE-MEMORY PROPERTIES; CELL-CULTURE; INJECTABLE HYDROGEL; BIOMEDICAL APPLICATIONS; ALPHA-CYCLODEXTRIN; GROWTH-FACTOR;

D O I：

10.1002/mabi.201800313

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Self-healing supramolecular hydrogels have emerged as a novel class of biomaterials that combine hydrogels with supramolecular chemistry to develop highly functional biomaterials with advantages including native tissue mimicry, biocompatibility, and injectability. These properties are endowed by the reversibly cross-linked polymer network of the hydrogel. These hydrogels have great potential for realizing yet to be clinically translated tissue engineering therapies. This review presents methods of self-healing supramolecular hydrogel formation and their uses in tissue engineering as well as future perspectives.

引用

页数：11

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