Maximizing the Yield of Lymph Node Cytology Lessons Learned From Rapid Onsite Evaluation of Image- and Endoscopic-Guided Biopsies of Hilar and Mediastinal Lymph Nodes

被引:19
作者
Santos, Gilda da Cunha [1 ,2 ]
Boerner, Scott L. [2 ]
Geddie, William R. [2 ]
机构
[1] Univ Toronto, Univ Hlth Network, Dept Lab Med & Pathobiol, Toronto, ON M5G 2C4, Canada
[2] Univ Hlth Network, Lab Med Program, Toronto, ON, Canada
关键词
lymph node; specimen handling; histocytological preparation techniques; biopsy; fine-needle; endoscopic transbronchial ultrasound; computed axial tomography; NON-HODGKIN-LYMPHOMA; NEEDLE-ASPIRATION; GROSS APPEARANCES; LUNG-CANCER; SAMPLES; MUTATIONS; EGFR;
D O I
10.1002/cncy.20166
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The evaluation of mediastinal and hilar lymph nodes for tissue diagnosis and staging of lung cancer is now commonly performed by minimally invasive, nonsurgical procedures such as computed tomography-guided fine-needle aspiration and endobronchial ultrasound-guided transbronchial needle aspiration. Ensuring that a sufficient quantity of cellular material has been acquired to enable multiple studies has become a priority issue in the era of personalized medicine, especially for patients with lung cancer, and this can be accomplished by rapid onsite evaluation (ROSE). This commentary focuses on the use of ROSE in guided procedures, especially for hilar and mediastinal lymph node aspirates, and describes an algorithm for handling these specimens. Cancer (Cancer Cytopathol) 2011;119:361-6. (C) 2071 American Cancer Society
引用
收藏
页码:361 / 366
页数:6
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