RADAR: a web server for RNA data analysis and research

被引：9

作者：

Khaladkar, Mugdha ^{[2
,3
]}

Bellofatto, Vivian ^{[4
]}

Wang, Jason T. L. ^{[2
,3
]}

Tian, Bin ^{[5
]}

Shapiro, Bruce A. ^{[1
]}

机构：

[1] NCI, Ctr Canc Res Nanobiol Program, Frederick, MD 21702 USA

[2] New Jersey Inst Technol, Bioinformat Program, Newark, NJ 07102 USA

[3] New Jersey Inst Technol, Dept Comp Sci, Newark, NJ 07102 USA

[4] Univ Med & Dent New Jersey, New Jersey Med Sch, Dept Microbiol & Mol Genet, Int Ctr Publ Hlth, Newark, NJ 07103 USA

[5] Univ Med & Dent New Jersey, New Jersey Med Sch, Dept Biochem & Mol Biol, Newark, NJ 07101 USA

来源：

NUCLEIC ACIDS RESEARCH | 2007年 / 35卷

关键词：

SECONDARY STRUCTURE PREDICTION; ALGORITHM; STABILITY; SEQUENCES;

D O I：

10.1093/nar/gkm253

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

RADAR is a web server that provides a multitude of functionality for RNA data analysis and research. It can align structure-annotated RNA sequences so that both sequence and structure information are taken into consideration during the alignment process. This server is capable of performing pair-wise structure alignment, multiple structure alignment, database search and clustering. In addition, RADAR provides two salient features: (i) constrained alignment of RNA secondary structures, and (ii) prediction of the consensus structure for a set of RNA sequences. RADAR will be able to assist scientists in performing many important RNA mining operations, including the understanding of the functionality of RNA sequences, the detection of RNA structural motifs and the clustering of RNA molecules, among others. The web server together with a software package for download is freely accessible at http://datalab.njit.edu/biodata/rna/RSmatch/server.htm and http://www.ccrnp.ncifcrf.gov/similar to bshapiro/.

引用

页码：W300 / W304

页数：5

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