One-Pot Synthesis of Quinazolinones via Iridium-Catalyzed Hydrogen Transfers

被引：251

作者：

Zhou, Jianguang ^{[1
]}

Fang, Jie ^{[1
]}

机构：

[1] Suzhou Novartis Pharma Technol Co Ltd, Chem & Analyt Dev, Changshu 215537, Jiangsu, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2011年 / 76卷 / 19期

关键词：

ASTERISK-IR COMPLEX; SECONDARY ALCOHOLS; FACILE SYNTHESIS; ALKYLATION; CONVERSION; OXIDATION; ALDEHYDES; AMINES;

D O I：

10.1021/jo201054k

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A one-pot oxidative cyclization of primary alcohols with o-aminobenzamides to quinazolinones was successfully achieved using [Cp*IrCl2](2) (Cp* = pentamethylcyclopentadienyl) as a catalyst under hydrogen transfer conditions.

引用

页码：7730 / 7736

页数：7

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