One-Pot Synthesis of Quinazolinones via Iridium-Catalyzed Hydrogen Transfers

被引：246
作者：
Zhou, Jianguang [1 ]
Fang, Jie [1 ]
机构：
[1] Suzhou Novartis Pharma Technol Co Ltd, Chem & Analyt Dev, Changshu 215537, Jiangsu, Peoples R China
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2011年 / 76卷 / 19期
关键词：
ASTERISK-IR COMPLEX; SECONDARY ALCOHOLS; FACILE SYNTHESIS; ALKYLATION; CONVERSION; OXIDATION; ALDEHYDES; AMINES;
D O I：
10.1021/jo201054k
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A one-pot oxidative cyclization of primary alcohols with o-aminobenzamides to quinazolinones was successfully achieved using [Cp*IrCl2](2) (Cp* = pentamethylcyclopentadienyl) as a catalyst under hydrogen transfer conditions.
引用
收藏
页码：7730 / 7736
页数：7
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