Microbial hydroxylation of kudtdiol with cultures of Cunninghamella echinulata

被引：8

作者：

Carrizo, R ^{[1
]}

Tonn, C ^{[1
]}

Guerreiro, E ^{[1
]}

机构：

[1] UNSL Chacabuco & Pedernera, CONICET, INTEQUI Quim Organ, RA-5700 San Luis, Argentina

来源：

NATURAL PRODUCT LETTERS | 1998年 / 12卷 / 04期

关键词：

biotransformation; hydroxylation; Cunninghamella echinulata; eudesmane; kudtdiol;

D O I：

10.1080/10575639808048301

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The 2 beta and 3 alpha-hydroxy derivatives, together with an epoxy derivative, were obtained in good yield by incubation of kudtdiol 1 with cultures of Cunninghamella echinulata.

引用

页码：271 / 276

页数：6

共 8 条

[1]

FIESER L, 1970, ORG SYNTH, V4, P440

[2] THE GASTRIC CYTOPROTECTIVE EFFECT OF SEVERAL SESQUITERPENE LACTONES [J].

GIORDANO, OS ;

GUERREIRO, E ;

PESTCHANKER, MJ ;

GUZMAN, J ;

PASTOR, D ;

GUARDIA, T .

JOURNAL OF NATURAL PRODUCTS, 1990, 53 (04) :803-809

[3] CYTOPROTECTIVE ACTIVITY OF MINOR CONSTITUENTS OF ARTEMISIA-DOUGLASIANA [J].

GUERREIRO, E ;

GARCIA, EE ;

PESTCHANKER, MJ ;

ENRIZ, RD ;

RODRIGUEZ, AM ;

MARIA, A ;

WENDEL, GH .

NATURAL PRODUCT LETTERS, 1995, 6 (04) :269-280

[4]

GUERREIRO E, 1979, AN ASOC QUIM ARGENT, V67, P119

[5]

POUS L, IN PRESS NATURAL PRO

[6]

PRUNA BR, 1969, APPL MICROBIOLOGY, V10, P524

[7] Structure-cytoprotective activity relationship of simple molecules containing an alpha,beta-unsaturated carbonyl system [J].

Rodriguez, AM ;

Enriz, RD ;

Santagata, LN ;

Jauregui, EA ;

Pestchanker, MJ ;

Giordano, OS .

JOURNAL OF MEDICINAL CHEMISTRY, 1997, 40 (12) :1827-1834

[8]

TERESA J P, 1980, Phytochemistry (Oxford), V19, P2155

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