Muscle fiber immaturity and inactivity reduce myonecrosis in Duchenne muscular dystrophy

被引：3

作者：

Kimura, S

Sugino, S

Ohtani, Y

Matsukura, M

Nishino, I

Ikezawa, M

Sakata, A

Kondo, Y

Yoshioka, K

Huard, J

Nonaka, I

Miike, T

机构：

[1] Kumamoto Univ, Sch Med, Dept Child Dev, Kumamoto 860, Japan

[2] Kumamoto City Hosp, Dept Pediat, Kumamoto, Japan

[3] Natl Ctr Neurol & Psychiat, Natl Inst Neurosci, Tokyo, Japan

[4] Childrens Hosp Pittsburgh, Sch Med, Dept Orthopaed Surg, Pittsburgh, PA 15213 USA

来源：

ANNALS OF NEUROLOGY | 1998年 / 44卷 / 06期

关键词：

D O I：

10.1002/ana.410440618

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We report on the first case of X-linked recessive myotubular myopathy (MTM1) coinciding with Duchenne muscular dystrophy (DMD). The muscle biopsy specimens of the patient show only the characteristic finding of MTM1, without the findings of DMD. We theorize that this was caused by the muscle fiber immaturity and inactivity.

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页码：967 / 971

页数：5

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