Preoperative comprehensive geriatric assessment and optimisation prior to elective arterial vascular surgery: a health economic analysis

被引:27
作者
Partridge, Judith S. L. [1 ,2 ]
Healey, Andrew [3 ]
Modarai, Bijan [4 ,5 ]
Harari, Danielle [1 ,2 ]
Martin, Finbarr C. [2 ]
Dhesi, Jugdeep K. [1 ,2 ,6 ]
机构
[1] Guys & St Thomas NHS Fdn Trust, Dept Ageing & Hlth, Perioperat Med Older People Undergoing Surg POPS, London, England
[2] Kings Coll London, Fac Life Sci & Med, Sch Populat Hlth & Environm Sci, London, England
[3] Kings Coll London, Ctr Implementat Sci & Kings Hlth Econ, London, England
[4] Kings Coll London, Sch Biomed Engn & Imaging Sci, Rayne Inst, London, England
[5] Guys & St Thomas NHS Fdn Trust, Acad Dept Vasc Surg, London, England
[6] UCL, Res Dept Targeted Intervent, Div Surg & Intervent Sci, London, England
关键词
cost-effectiveness; health-related quality of life (HRQoL); quality-adjusted life-years (QALY); older surgical patients; perioperative medicine; collaborative care; frailty; EUROQOL; CARE; UNCERTAINTY; SURVIVAL; QUALITY;
D O I
10.1093/ageing/afab094
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Background: increasing numbers of older people are undergoing vascular surgery. Preoperative comprehensive geriatric assessment and optimisation (CGA) reduces postoperative complications and length of hospital stay. Establishing CGA-based perioperative services requires health economic evaluation prior to implementation. Through a modelling-based economic evaluation, using data from a single site clinical trial, this study evaluates whether CGA is a cost-effective alternative to standard preoperative assessment for older patients undergoing elective arterial surgery. Methods: an economic evaluation, using decision-analytic modelling, comparing preoperative CGA and optimisation with standard preoperative care, was undertaken in older patients undergoing elective arterial surgery. The incremental net health benefit of CGA, expressed in terms of quality-adjusted life-years (QALYs), was used to evaluate cost-effectiveness. Results: CGA is a cost-effective substitute for standard preoperative care in elective arterial surgery across a range of cost-effectiveness threshold values. An incremental net benefit of 0.58 QALYs at a cost-effectiveness threshold of 30k pound, 0.60 QALYs at a threshold of 20k pound and 0.63 QALYs at a threshold of 13k pound was observed. Mean total pre- and postoperative health care utilisation costs were estimated to be 1,165 pound lower for CGA patients largely accounted for by reduced postoperative bed day utilisation. Conclusion: this study demonstrates a likely health economic benefit in addition to the previously described clinical benefit of employing CGA methodology in the preoperative setting in older patients undergoing arterial surgery. Further evaluation should examine whether CGA-based perioperative services can be effectively implemented and achieve the same clinical and health economic outcomes at scale.
引用
收藏
页码:1770 / 1777
页数:8
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