[1] Houston Methodist Res Inst, Dept Nanomed, Houston, TX 77030 USA
[2] Univ Politecn Marche, Dept Life & Environm Sci, Ancona, Italy
[3] Fdn IRCCS Policlin San Matteo, Pain Therapy Serv, Pavia, Italy
[4] Natl Res Council Italy, Inst Sci & Technol Ceram, Bioceram & Biohybrid Mat, Faenza, Italy
[5] Houston Methodist Hosp, Dept Orthoped Surg, Houston, TX USA