Visible-Light-Catalyzed [3+1+2] Coupling Annulations for the Synthesis of Unsymmetrical Trisubstituted Amino-1,3,5-triazines

被引：25

作者：

Guo, Wei ^{[1
]}

Zhao, Mingming ^{[1
]}

Du, Chengtang ^{[1
]}

Zheng, Lvyin ^{[1
]}

Li, Luo ^{[1
]}

Chen, Liping ^{[1
]}

Tao, Kailiang ^{[1
]}

Tan, Wen ^{[1
]}

Xie, Zhen ^{[1
]}

Cai, Liuhuan ^{[1
]}

Fan, Xiaolin ^{[1
]}

Zhang, Kai ^{[2
]}

机构：

[1] Gannan Normal Univ, Key Lab Organopharmaceut Chem Jiangxi Prov, Ganzhou 341000, Peoples R China

[2] Huanggang Normal Univ, Sch Chem & Chem Engn, Hubei Key Lab Proc & Applicat Catalyt Mat, Huangzhou 438000, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2019年 / 84卷 / 23期

基金：

中国国家自然科学基金;

关键词：

SUBSTITUTED 1,3,5-TRIAZINES; MEDIATED SYNTHESIS; AMIDINES; ALCOHOLS; INHIBITION; DESIGN; FUNCTIONALIZATION; CYCLIZATION; GUANAMINES; LIGAND;

D O I：

10.1021/acs.joc.9b02514

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A visible-light catalyzed [3 + 1 + 2] annulation for the synthesis of unsymmetrical trisubstituted amino-1,3,5-triazines from amidines, isothiocyanates, and 1,1,3,3-tetramethylguanidines has been developed. This method exhibits the advantages of easily available starting materials, insensitive to air and moisture, wide substrate scopes, high step economy, mild, metal- and ligand-free conditions, which has potential applications in the organic, medicinal, and material chemistry.

引用

页码：15508 / 15519

页数：12

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