Aqueous Reaction of Alcohols, Organohalides, and Odorless Sodium Thiosulfate under Transition-Metal-Free Conditions: Synthesis of Unsymmetrical Aryl Sulfides via Dual C-S Bond Formation

被引：20

作者：

Liu, Bei-Bei ^{[1
,2
]}

Chu, Xue-Qiang ^{[1
,2
]}

Liu, Huan ^{[1
,2
]}

Yin, Ling ^{[3
]}

Wang, Shun-Yi ^{[1
,2
]}

Ji, Shun-Jun ^{[1
,2
]}

机构：

[1] Soochow Univ, Key Lab Organ Synth Jiangsu Prov, Coll Chem Chem Engn & Mat Sci, Suzhou 215123, Peoples R China

[2] Soochow Univ, Collaborat Innovat Ctr Suzhou Nano Sci & Technol, Suzhou 215123, Peoples R China

[3] Jining Univ, Dept Chem & Chem Engn, Qufu 273155, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2017年 / 82卷 / 19期

基金：

中国国家自然科学基金;

关键词：

ELEMENTAL SULFUR; BUNTE SALTS; COUPLING REACTIONS; SULFONES; 3-SULFENYLATION; ACTIVATION; REDUCTION; CHLORIDES; INDOLES; OXIDANT;

D O I：

10.1021/acs.joc.7b01653

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A transition-metal-free process for the synthesis of unsymmetrical aryl sulfides via dual C-S bond formation by a one-pot three-component reaction of alcohols, organohalides, and odorless sodium thiosulfate in water has been developed. In addition, the aryl sulfides could also be prepared by the reaction of the corresponding alcohols and Bunte salts under the identical conditions. This protocol provides a green and efficient manner for the construction of various unsymmetrical aryl sulfides.

引用

页码：10174 / 10180

页数：7

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