The intervention, the patient and the illness-Personalizing non-invasive brain stimulation in psychiatry

被引:19
作者
Padberg, Frank [1 ,2 ]
Bulubas, Lucia [1 ,2 ,3 ]
Mizutani-Tiebel, Yuki [1 ,2 ]
Burkhardt, Gerrit [1 ,2 ]
Kranz, Georg S. [4 ,5 ]
Koutsouleris, Nikolaos [1 ,6 ]
Kambeitz, Joseph [7 ,8 ]
Hasan, Alkomiet [2 ,9 ,11 ]
Takahashi, Shun [10 ]
Keeser, Daniel [1 ,2 ]
Goerigk, Stephan [1 ,2 ,12 ,13 ]
Brunoni, Andre R. [14 ,15 ,16 ]
机构
[1] Ludwig Maximilians Univ Munchen, Univ Hosp, Dept Psychiat & Psychotherapy, Nussbaumstr 7, D-80336 Munich, Germany
[2] Ctr Noninvas Brain Stimulat Munich Augsburg CNBS, Munich, Germany
[3] Int Max Planck Res Sch Translat Psychiat IMPRS TP, Munich, Germany
[4] Hong Kong Polytech Univ, Dept Rehabil Sci, Hong Kong, Peoples R China
[5] Med Univ Vienna, Dept Psychiat & Psychotherapy, Vienna, Austria
[6] Max Planck Inst Psychiat, Munich, Germany
[7] Univ Cologne, Fac Med, Dept Psychiat, D-50937 Cologne, Germany
[8] Univ Hosp Cologne, D-50937 Cologne, Germany
[9] Univ Augsburg, Med Fac, Dept Psychiat Psychotherapy & Psychosomat, BKH Augsburg, Dr Mack Str 1, D-86156 Augsburg, Germany
[10] Wakayama Med Univ, Dept Neuropsychiat, 811-1 Kimiidera, Wakayama 6410012, Japan
[11] LMU Hosp, Dept Clin Radiol, Munich, Germany
[12] Ludwig Maximilians Univ Munchen, Dept Psychol Methodol & Assessment, Leopoldstr 13, D-80802 Munich, Germany
[13] Univ Appl Sci, Hsch Fresenius, Infanteriestr 11A, D-80797 Munich, Germany
[14] Univ Sao Paulo, Inst Nacl Biomarcadores Neuropsiquiatr INBioN, Dept & Inst Psychiat, Fac Med,Lab Neurosci LIM 27, Sao Paulo, Brazil
[15] Univ Sao Paulo, Fac Med, Dept Internal Med, Av Prof Lineu Prestes 2565, BR-05508000 Sao Paulo, Brazil
[16] Univ Sao Paulo, Univ Hosp, Av Prof Lineu Prestes 2565, BR-05508000 Sao Paulo, Brazil
基金
欧盟第七框架计划;
关键词
Precision medicine; Non-invasive brain stimulation; NIBS; Repetitive transcranial magnetic stimulation; rTMS; Transcranial direct current stimulation; tDCS; Affective disorders; Major depression; TRANSCRANIAL MAGNETIC STIMULATION; MAJOR DEPRESSIVE DISORDER; DORSOLATERAL PREFRONTAL CORTEX; THETA-BURST STIMULATION; MEDICATION-RESISTANT DEPRESSION; RESTING-STATE CONNECTIVITY; ANTERIOR CINGULATE CORTEX; INDUCED PLASTICITY; CLINICAL-OUTCOMES; NEGATIVE SYMPTOMS;
D O I
10.1016/j.expneurol.2021.113713
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Current hypotheses on the therapeutic action of non-invasive brain stimulation (NIBS) in psychiatric disorders build on the abundant data from neuroimaging studies. This makes NIBS a very promising tool for developing personalized interventions within a precision medicine framework. NIBS methods fundamentally vary in their neurophysiological properties. They comprise repetitive transcranial magnetic stimulation (rTMS) and its variants (e.g. theta burst stimulation - TBS) as well as different types of transcranial electrical stimulation (tES), with the largest body of evidence for transcranial direct current stimulation (tDCS). In the last two decades, significant conceptual progress has been made in terms of NIBS targets, i.e. from single brain regions to neural circuits and to functional connectivity as well as their states, recently leading to brain state modulating closed-loop approaches. Regarding structural and functional brain anatomy, NIBS meets an individually unique constellation,
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页数:14
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