Background: Epoprostenol infusion is the strongest and most convincing therapeutic strategy for severe pulmonary arterial hypertension (PAH). This study investigated the gastrointestinal side effects of epoprostenol. Methods and Results: The study group of 12 patients treated with epoprostenol (epoprostenol group) and 4 patients without epoprostenol (control group) underwent stomach barium examination, which revealed that the prevalence of giant fold gastritis was significantly higher in the patients treated with epoprostenol (75% in epoprostenol group vs. 0% in control group; P=0.019). Conclusions: Giant fold gastritis may be an important side effect of epoprostenol infusion.
机构:
Keio Univ, Sch Med, Dept Internal Med, Div Rheumatol,Shinjuku Ku, Tokyo 1608582, JapanKeio Univ, Sch Med, Dept Internal Med, Div Rheumatol,Shinjuku Ku, Tokyo 1608582, Japan
Shirai, Yuichiro
Yasuoka, Hidekata
论文数: 0引用数: 0
h-index: 0
机构:
Keio Univ, Sch Med, Dept Internal Med, Div Rheumatol,Shinjuku Ku, Tokyo 1608582, JapanKeio Univ, Sch Med, Dept Internal Med, Div Rheumatol,Shinjuku Ku, Tokyo 1608582, Japan
Yasuoka, Hidekata
Takeuchi, Tsutomu
论文数: 0引用数: 0
h-index: 0
机构:
Keio Univ, Sch Med, Dept Internal Med, Div Rheumatol,Shinjuku Ku, Tokyo 1608582, JapanKeio Univ, Sch Med, Dept Internal Med, Div Rheumatol,Shinjuku Ku, Tokyo 1608582, Japan
Takeuchi, Tsutomu
Satoh, Toru
论文数: 0引用数: 0
h-index: 0
机构:
Keio Univ, Sch Med, Dept Internal Med, Div Cardiol,Shinjuku Ku, Tokyo 1608582, Japan
Kyorin Univ, Sch Med, Dept Cardiol, Mitaka, Tokyo 1818611, JapanKeio Univ, Sch Med, Dept Internal Med, Div Rheumatol,Shinjuku Ku, Tokyo 1608582, Japan
Satoh, Toru
Kuwana, Masataka
论文数: 0引用数: 0
h-index: 0
机构:
Keio Univ, Sch Med, Dept Internal Med, Div Rheumatol,Shinjuku Ku, Tokyo 1608582, JapanKeio Univ, Sch Med, Dept Internal Med, Div Rheumatol,Shinjuku Ku, Tokyo 1608582, Japan