Synchronous collision malignant melanoma and adenocarcinoma of the rectum

被引:10
作者
Dias, A. R. [2 ]
Pinto, R. A. [1 ,2 ]
Mory, E. [2 ]
Silva, I. C. [3 ]
Siqueira, S. A. C. [3 ]
Nahas, S. C. [2 ]
Cecconello, I. [2 ]
Wexner, S. D. [1 ]
机构
[1] Cleveland Clin Florida, Dept Colorectal Surg, Weston, FL 33331 USA
[2] Univ Sao Paulo, Sch Med, Dept Gastroenterol, Div Colorectal Surg,Hosp Clin, Sao Paulo, Brazil
[3] Univ Sao Paulo, Sch Med, Dept Pathol, Hosp Clin, Sao Paulo, Brazil
关键词
Collision tumor; Melanoma; Adenocarcinoma; Physiopathology; PAPILLARY THYROID-CARCINOMA; STROMAL FIBROBLASTS; TUMOR-STROMA; STEM-CELL; CANCER; PROGRESSION; BREAST; DIFFERENTIATION;
D O I
10.1007/s10151-010-0571-6
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
"Collision tumors" consist of two independent but coexisting tumors. This uncommon situation might be easily mistaken for a composite tumor where one histogenetic event originates from two apparently distinct neoplasms. Colorectal collisions are particularly unusual; here, we report the exceedingly rare case of a 61-year-old man with malignant melanoma and adenocarcinoma colliding in the rectum. Collision tumors have an idiopathic pathophysiology and in fact "accidental meeting" is accepted by many authors. This article discusses the concepts about cancer development, which are overlooked by this hypothesis, another theory to explain that this rare occurrence involves microenvironment changes.
引用
收藏
页码:181 / 184
页数:4
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