Bisphosphonates and avascular necrosis of the mandible: Case report and review of the literature

被引：4

作者：

Murray, Dylan J. ^{[1
,2
]}

Vesely, Martin J. J. ^{[1
,2
]}

Novak, Christine B. ^{[2
]}

Irish, Jonathan ^{[2
,3
]}

Crump, Michael ^{[4
]}

Neligan, Peter C. ^{[1
,2
]}

机构：

[1] Univ Toronto, Div Plast Surg, Univ Hlth Network, Toronto Gen Hosp, Toronto, ON M5G 2C4, Canada

[2] Univ Hlth Network, Wharton Head & Neck Ctr, Toronto, ON, Canada

[3] Univ Toronto, Univ Hlth Network, Dept Otolaryngol Head & Neck Surg, Toronto, ON M5G 2C4, Canada

[4] Univ Toronto, Univ Hlth Network, Dept Med Oncol & Hematol, Toronto, ON, Canada

来源：

JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY | 2008年 / 61卷 / 01期

关键词：

bisphosphonates; avascular necrosis; cancer; head and neck; case report;

D O I：

10.1016/j.bjps.2006.06.017

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Background: Avascular necrosis of the mandible or maxilla is being recognized with increasing frequency in patients who are being treated with bisphosphonates for metastatic cancers. Methods and results: A patient who was treated for avascular necrosis following treatment with bisphosphonates for multiple myeloma is presented. Conclusion: Prophylactic and preventative measures should be instituted prior to commencing treatment with bisphosphonates to minimize the risk of developing avascular necrosis. (c) 2006 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

引用

页码：94 / 98

页数：5

共 23 条

[1] Alendronate in the treatment of avascular necrosis of the hip [J].

Agarwala, S ;

Sule, A ;

Pai, BU ;

Joshi, VR .

RHEUMATOLOGY, 2002, 41 (03) :346-347

[2] Avascular jaw osteonecrosis in association with cancer chemotherapy: series of 10 cases [J].

Bagan, JV ;

Murillo, J ;

Jimenez, Y ;

Poveda, R ;

Milian, MA ;

Sanchis, JM ;

Silvestre, FJ ;

Scully, C .

JOURNAL OF ORAL PATHOLOGY & MEDICINE, 2005, 34 (02) :120-123

[3]

Durie BGM, 2005, NEW ENGL J MED, V353, P99

[4] Bisphosphonate osteochemonecrosis (bis-phossy jaw): Is this phossy jaw of the 21st century? [J].

Hellstein, JW ;

Marek, CL .

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 2005, 63 (05) :682-689

[5] Bis-phossy jaw, phossy jaw, and the 21st century: Bisphosphonate-associated complications of the jaws [J].

Hellstein, JW ;

Marek, CL .

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 2004, 62 (12) :1563-1565

[6] Differences in antimicrobial activity of four commercial 0.12% chlorhexidine mouthrinse formulations:: an in vitro contact test and salivary bacterial counts study [J].

Herrera, D ;

Roldán, S ;

Santacruz, I ;

Santos, S ;

Masdevall, M ;

Sanz, M .

JOURNAL OF CLINICAL PERIODONTOLOGY, 2003, 30 (04) :307-314

[7] INHIBITION OF OSTEOCLAST-LIKE CELL-FORMATION BY BISPHOSPHONATES IN LONG-TERM CULTURES OF HUMAN-BONE MARROW [J].

HUGHES, DE ;

MACDONALD, BR ;

RUSSELL, RGG ;

GOWEN, M .

JOURNAL OF CLINICAL INVESTIGATION, 1989, 83 (06) :1930-1935

[8] Toward new horizons: The future of bisphosphonate therapy [J].

Lipton, A .

ONCOLOGIST, 2004, 9 :38-47

[9] OSTEORADIONECROSIS - A NEW CONCEPT OF ITS PATHO-PHYSIOLOGY [J].

MARX, RE .

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 1983, 41 (05) :283-288

[10] Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: A growing epidemic [J].

Marx, RE .

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 2003, 61 (09) :1115-1117

← 1 2 3 →