Healing of intracranial aneurysms with bioactive coils

被引：7
作者：
Feng, L [1 ]
Vinuela, F [1 ]
Murayama, Y [1 ]
机构：
[1] Univ Calif Los Angeles, Dept Radiol Sci, Los Angeles, CA 90095 USA
来源：
NEUROSURGERY CLINICS OF NORTH AMERICA | 2005年 / 16卷 / 03期
关键词：
D O I：
10.1016/j.nec.2005.03.001
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Inadequate healing is an important mechanism for aneurysm development and recanalization after embolization. Matrix coils have been shown by experimental studies to enhance vascular repair and fibrosis, thus reducing the risk of recanalization. The clinical application of Matrix coils represents the transition from pure mechanical occlusion to adjunct biologic healing of aneurysms. Our preliminary clinical experience reveals evidence of a healing response in aneurysms treated with Matrix coils. This technology can be further improved through the incorporation of new knowledge on the molecular pathogenesis of aneurysms and the cellular and molecular mechanisms of healing.
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页码：487 / +
页数：15
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