Synthesis and bioactivity of some new 3-(pyrazin-2′-yl)-6-aryl-5-pyrazinoyl-(6H)-1,2,4-triazolo (3,4-b) (1,3,4)-thiadiazolidines

被引：0
|
作者：
Gupta, VRM
Raviprakash, P
Varnekar, RB
Srinivasulu, N
Udupi, RH [1 ]
机构：
[1] NET Coll Pharm, Dept Pharmaceut Chem, Raichur 584103, India
[2] VL Coll Pharm, Dept Pharmaceut Chem, Raichur 584101, India
来源：
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 2005年 / 14卷 / 04期
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D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Condensation of 3-(pyrazin-2'-yl)-4-(N-pyrazin-2"-yl carboxamido)-5-mercapto 1,2,4-triazole (3) with aromatic carboxaldehydes furnished in one step the cyclic products 3(pyrazin-2'-yl)-6-aryl/substituted aryl-5-pyrazinoyl-(6H)-1,2,4-triazolo (3,4-b) (1,3,4) thiadiazolidines (4a(1)-a(14)). The antibacterial, antifungal, antiinflammatory and analgesic activities of some of the compounds have been evaluated.
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页码：335 / 338
页数：4
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