Selective Functionalization of Hollow Nanospheres with Acid and Base Groups for Cascade Reactions

被引：62

作者：

Gao, Jinsuo ^{[1
]}

Zhang, Xueying ^{[1
]}

Lu, Yong ^{[1
]}

Liu, Shaomin ^{[2
]}

Liu, Jian ^{[2
]}

机构：

[1] Dalian Univ Technol, Key Lab Ind Ecol & Environm Engn MOE, Sch Environm Sci & Technol, State Key Lab Fine Chem, Dalian 116024, Peoples R China

[2] Curtin Univ, Dept Chem Engn, Perth, WA 6845, Australia

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2015年 / 21卷 / 20期

基金：

中国国家自然科学基金;

关键词：

cascade reaction; hollow nanosphere; nanostructures; mesoporous materials; selective functionalization; MESOPOROUS SILICA NANOPARTICLES; EXTERNAL SURFACES; DRUG-DELIVERY; SHELL; CORE; CATALYSTS; METAL; NANOSTRUCTURES; NANOREACTOR; ANTIBIOTICS;

D O I：

10.1002/chem.201500532

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The inner-surface functionalization of hollow silica spheres has rarely been reported and is still a challenging topic. Herein, we report a deacetalization-Henry cascade reaction catalyzed by dual-functionalized mesoporous silica hollow nanospheres with basic amine groups (-NH2) on the internal shell and carboxylic acid groups (-COOH) on the external shell. The selective functionalization has been realized by a combination of "step-by-step post-grafting" and "cationic surfactant-assisted selective etching" strategy. Compared to unisolated catalyst, the selectively isolated acidic and basic dual catalyst provides excellent catalytic performance for the deacetalization-Henry cascade reaction in terms of both activity (>99%) and selectivity (95 %).

引用

页码：7403 / 7407

页数：5