Selective Functionalization of Hollow Nanospheres with Acid and Base Groups for Cascade Reactions

被引:63
作者
Gao, Jinsuo [1 ]
Zhang, Xueying [1 ]
Lu, Yong [1 ]
Liu, Shaomin [2 ]
Liu, Jian [2 ]
机构
[1] Dalian Univ Technol, Key Lab Ind Ecol & Environm Engn MOE, Sch Environm Sci & Technol, State Key Lab Fine Chem, Dalian 116024, Peoples R China
[2] Curtin Univ, Dept Chem Engn, Perth, WA 6845, Australia
基金
中国国家自然科学基金;
关键词
cascade reaction; hollow nanosphere; nanostructures; mesoporous materials; selective functionalization; MESOPOROUS SILICA NANOPARTICLES; EXTERNAL SURFACES; DRUG-DELIVERY; SHELL; CORE; CATALYSTS; METAL; NANOSTRUCTURES; NANOREACTOR; ANTIBIOTICS;
D O I
10.1002/chem.201500532
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The inner-surface functionalization of hollow silica spheres has rarely been reported and is still a challenging topic. Herein, we report a deacetalization-Henry cascade reaction catalyzed by dual-functionalized mesoporous silica hollow nanospheres with basic amine groups (-NH2) on the internal shell and carboxylic acid groups (-COOH) on the external shell. The selective functionalization has been realized by a combination of "step-by-step post-grafting" and "cationic surfactant-assisted selective etching" strategy. Compared to unisolated catalyst, the selectively isolated acidic and basic dual catalyst provides excellent catalytic performance for the deacetalization-Henry cascade reaction in terms of both activity (>99%) and selectivity (95 %).
引用
收藏
页码:7403 / 7407
页数:5
相关论文
共 51 条
[1]  
[Anonymous], 2012, ANGEW CHEM, V124, P8498
[2]  
[Anonymous], 2008, ANGEW CHEM, V120, P2737
[3]  
[Anonymous], 2011, ANGEW CHEM, V123, P687
[4]  
[Anonymous], 2012, ANGEW CHEM, V124, P9298
[5]  
[Anonymous], 2008, ANGEW CHEM, V120, P5890
[6]  
[Anonymous], 2014, ANGEW CHEM, V126, P2989
[7]  
Bruhwiler D., 2010, NANOSCALE, V2, P887
[8]   Tuning acid-base cooperativity to create next generation silica-supported organocatalysts [J].
Brunelli, Nicholas A. ;
Jones, Christopher W. .
JOURNAL OF CATALYSIS, 2013, 308 :60-72
[9]   Cooperative Catalysis with Acid-Base Bifunctional Mesoporous Silica: Impact of Grafting and Co-condensation Synthesis Methods on Material Structure and Catalytic Properties [J].
Brunelli, Nicholas A. ;
Venkatasubbaiah, Krishnan ;
Jones, Christopher W. .
CHEMISTRY OF MATERIALS, 2012, 24 (13) :2433-2442
[10]   Facile and Scalable Synthesis of Tailored Silica "Nanorattle" Structures [J].
Chen, Dong ;
Li, Linlin ;
Tang, Fangqiong ;
Qi, Shuo .
ADVANCED MATERIALS, 2009, 21 (37) :3804-3807