Arginine vasopressin (AVP): a review of its historical perspectives, current research and multifunctional role in the hypothalamo-hypophysial system

被引:72
作者
Rotondo, Fabio [1 ]
Butz, Henriett [1 ]
Syro, Luis V. [2 ,3 ]
Yousef, George M. [1 ]
Di Ieva, Antonio [4 ]
Restrepo, Lina M. [5 ]
Quintanar-Stephano, Andres [6 ]
Berczi, Istvan [7 ]
Kovacs, Kalman [1 ]
机构
[1] St Michaels Hosp, Li Ka Shing Knowledge Inst, Keenan Res Ctr Biomed Sci, Div Pathol,Dept Lab Med, 209 Victoria St, Toronto, ON M5B 1T8, Canada
[2] Hosp Pablo Tobon Uribe, Dept Neurosurg, Medellin, Colombia
[3] Clin Medellin, Medellin, Colombia
[4] Macquarie Univ Hosp, Dept Neurosurg, Sydney, NSW, Australia
[5] Clin Medellin, Div Endocrinol, Medellin, Colombia
[6] Univ Autonoma Aguascalientes, Ctr Ciencias Basicas, Dept Fisiol & Farmacol, Aguascalientes, Mexico
[7] Univ Manitoba, Fac Med, Dept Immunol, Winnipeg, MB, Canada
关键词
Arginine vasopressin; Corticotroph cells; Hypothalamus; Pituitary; Receptors; CORTICOTROPIN-RELEASING-FACTOR; NEUROINTERMEDIATE PITUITARY LOBECTOMY; NEPHROGENIC DIABETES-INSIPIDUS; DESMOPRESSIN STIMULATION TEST; CUSHINGS-DISEASE; ADRENAL AXIS; DIFFERENTIAL-DIAGNOSIS; ADRENOCORTICOTROPIN SECRETION; PARAVENTRICULAR NUCLEUS; HORMONE-SECRETION;
D O I
10.1007/s11102-015-0703-0
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
This publication reviews the function of arginine vasopressin and focuses on the morphologic and functional correlation between the hormone and its effect on stress, the hypophysial-adrenocortical axis, neuroimmune responses, renal function and corticotroph pituitary tumors. A literature review was performed using various search engines for information regarding the morphology and the multifunctional role of arginine vasopressin. Although a large number of studies were published discussing these interactions, there are several important areas that are still obscure. The questions of how does arginine vasopressin affect the morphology and function of these various areas, and how does the secretion of ACTH and adrenocortical hormones influence the morphology of arginine vasopressin-producing cells and their hormone secretion requires further investigation.
引用
收藏
页码:345 / 355
页数:11
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