Synthesis and cytotoxicity against human cancer cells of novel diazenecarboxamides

被引：0

作者：

Pieters, L

Kosmrlj, J

Lenarsic, R

Kocevar, M

Polanc, S

机构：

[1] Univ Ljubljana, Fac Chem & Chem Technol, SI-1000 Ljubljana, Slovenia

[2] Univ Instelling Antwerp, Dept Pharmaceut Sci, B-2610 Antwerp, Belgium

来源：

ARKIVOC | 2001年 / 2卷

关键词：

diazenecarboxamides; synthesis; cytotoxic activity;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis as well as the cytotoxic activity of a series of diazenecarboxamides 1a-1j, which are stable representatives of the diazene family, in a human cancer cell line panel are described. Compounds 1j and especially 1g showed a high cytotoxic activity against some leukemia cell lines, and can be considered as new leads for further development.

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收藏

页码：U63 / U70

页数：8

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