Group A Streptococcal Infections

被引:31
作者
Langlois, Debra M. [1 ]
Andreae, Margie [1 ]
机构
[1] Univ Michigan, Sch Med, Div Gen Pediat, Dept Pediat & Communicable Dis, Ann Arbor, MI 48109 USA
关键词
D O I
10.1542/pir.32-10-423
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
• GAS is a common cause of upper respiratory tract and skin infections. • Based on strong research evidence, (1) throat culture is the gold standard for diagnosing GAS pharyngitis. • Based on strong research evidence, (1) oral penicillin V K is the antibiotic treatment of choice for GAS pharyngitis because of its efficacy, safety, and narrow spectrum. • Based on strong research evidence, (2) primary prevention of complications of GAS such as ARF involves prompt diagnosis and antibiotic treatment of GAS pharyngitis. • GAS nonsuppurative and suppurative complications may occur and are mediated by interactions between GAS antigens or exotoxins and the patient's immune system.
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页码:423 / 430
页数:8
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