Pediatric tramadol ingestion resulting in seizurelike activity - A case series

被引：9

作者：

Mazor, Suzan S. ^{[1
,2
,3
]}

Feldman, Kenneth W. ^{[1
]}

Sugar, Naomi F. ^{[1
]}

Sotero, Marcio ^{[1
,2
,4
]}

机构：

[1] Univ Washington, Sch Med, Dept Pediat, Seattle, WA 98195 USA

[2] Univ Washington, Sch Med, Dept Emergency Med, Seattle, WA USA

[3] Univ Washington, Sch Med, Dept Toxicol, Seattle, WA USA

[4] Univ Washington, Sch Med, Dept Neurol, Seattle, WA USA

来源：

PEDIATRIC EMERGENCY CARE | 2008年 / 24卷 / 06期

关键词：

tramadol; poisoning; seizures; dystonia;

D O I：

10.1097/PEC.0b013e318177a6ed

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Tramadol has been reported to cause seizures in therapeutic dosing and in overdose. We present a series of 2 infants poisoned with tramadol, both presenting with abnormal neurologic findings: either seizures or seizurelike activity. Tramadol poisoning should be considered in the differential diagnosis of dystonia and seizures.

引用

页码：380 / 381

页数：2

共 14 条

[1] Utility of comprehensive toxicologic screens in children [J].

Belson, MG ;

Simon, HK .

AMERICAN JOURNAL OF EMERGENCY MEDICINE, 1999, 17 (03) :221-224

[2]

BIANCHETTI MG, 1988, HELV PAEDIATR ACTA, V43, P241

[3] Danger of flumazenil use in pediatric status epilepticus [J].

Brierley, J .

PEDIATRIC EMERGENCY CARE, 2006, 22 (03) :168-169

[4]

Freye E, 1998, SCHMERZ, V12, P19, DOI 10.1007/s004820050123

[5] Seizures reported with tramadol [J].

Kahn, LH ;

Alderfer, RJ ;

Graham, DJ .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1997, 278 (20) :1661-1661

[6]

MAFFEI FA, 2006, EMEDICINE

[7]

Marquardt K., 2002, Journal of Toxicology Clinical Toxicology, V40, P609

[8]

MARQUARDT K, 2001, CLIN TOXICOL, V39, P487

[9]

RARITAN NJ, 1999, ULTRAM ORAL TABLET P

[10] SEVERE CEREBRAL DEPRESSION AFTER INTOXICATION WITH TRAMADOL IN A 6-MONTH-OLD INFANT [J].

RIEDEL, F ;

VONSTOCKHAUSEN, HB .

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1984, 26 (05) :631-632

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