Synthesis and Herbicidal Activity of Diphenyl Ether Derivatives Containing Unsaturated Carboxylates

被引：27

作者：

Yu, Haibo ^{[1
]}

Yang, Huibin ^{[1
]}

Gui, Dongliang ^{[1
]}

Lv, Liang ^{[1
]}

Li, Bin ^{[1
]}

机构：

[1] Shenyang Res Inst Chem Ind Co Ltd, State Key Lab Discovery & Dev Novel Pesticide, Shenyang 110021, Peoples R China

来源：

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 2011年 / 59卷 / 21期

关键词：

Protoporphyrinogen oxidase; diphenyl ether; unsaturated carboxylate; synthesis; herbicide; PROTOPORPHYRINOGEN OXIDASE-INHIBITORS; OXIDIZING ACTIVITIES; ETHYL; MECHANISM; DESIGN; MODE;

D O I：

10.1021/jf2039444

中图分类号：

S [农业科学];

学科分类号：

09 ;

摘要：

A series of novel diphenyl ether derivatives containing unsaturated carboxylates were designed and synthesized Their structures were identified by H-1 nuclear magnetic resonance and elemental analyses The bioassays indicated that the compounds 5b and 5c exhibited good herbicidal activities against velvetleaf at a concentration of 30-40 g/hm(2) The relationship between structure and herbicidal activity was also discussed Among unsaturated carboxylates group; butenoate is the most promising one Amonst them, 4-ethoxy-4-oxobutenyl 5-(2-chloro-4-(trifluoromethyl)phenoxy)-2-nitrobenzoate 5b was identified as the most promising candidate due to its high protoporphyrinogen IX oxidase inhibition effect (pI(50) = 6 64) and good herbicidal activity against broadleaf weeds with selectivity to soybean and low toxicity to mammals

引用

页码：11718 / 11726

页数：9