Versatile direct synthesis of oligosubstituted pyrroles by cycloaddition of α-metalated isocyanides to acetylenes

被引：220
作者：
Larionov, OV [1 ]
de Meijere, A [1 ]
机构：
[1] Univ Gottingen, Inst Organ & Biomol Chem, D-37077 Gottingen, Germany
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2005年 / 44卷 / 35期
关键词：
cesium; copper; heterocycles; homogeneous catalysis; isocyanides;
D O I：
10.1002/anie.200502140
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
(Chemical Equation Presented) Acceptor-substituted pyrroles can be prepared from acetylenes and isocyanides in an efficient and direct manner by a formal cycloaddition under basic conditions or, even simpler, in the presence of catalytic amounts of nanosize copper powder or copper(I) benzenethiolate. © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.
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页码：5664 / 5667
页数：4
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