NEXT GENERATION SEQUENCING AND MULTI-GENE PANEL TESTING: IMPLICATIONS FOR THE ONCOLOGY NURSE

被引：8
作者：
Kelly, Patricia A. [1 ]
机构：
[1] Texas Hlth Presbyterian Hosp Dallas, 8200 Walnut Hill Lane, Dallas, TX 75231 USA
来源：
SEMINARS IN ONCOLOGY NURSING | 2017年 / 33卷 / 02期
关键词：
genetic testing; next-generation sequencing; multi-gene panels; hereditary breast cancer; personalized health care; ATM gene; CANCER-RISK-ASSESSMENT; CONTRALATERAL BREAST-CANCER; BRCA2 MUTATION CARRIERS; SUSCEPTIBILITY; SOCIETY; GENE; PREDICTION; UPDATE; WECARE; MODEL;
D O I：
10.1016/j.soncn.2017.02.007
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
OBJECTIVES: To review past, current, and future events in genetics and discuss how genetic testing information personalizes cancer screening, detection, and treatment. A case study is presented to illustrate key points. DATA SOURCES: National guidelines, evidence-based summaries, peer-reviewed studies, editorials, and web sites. CONCLUSION: Multi-gene testing using next-generation sequencing has changed the landscape for hereditary cancer syndromes.
引用
收藏
页码：208 / 218
页数：11
相关论文
共 57 条
[1]   ATM and breast cancer susceptibility [J].
Ahmed, M. ;
Rahman, N. .
ONCOGENE, 2006, 25 (43) :5906-5911
[2]  
American Nurses Credentialing Center (ANCC), ADV GEN NURS
[3]  
[Anonymous], ENH BREAST OV CANC C
[4]  
[Anonymous], 2016, NCCN Clin Pract Guidel Oncol
[5]  
[Anonymous], 1999, GENEREVIEWS
[6]  
[Anonymous], ONL MEND INH MAN OMI
[7]  
[Anonymous], OBSTET GYNECOL
[8]  
[Anonymous], NCI CANC GEN SERV DI
[9]  
[Anonymous], 2017, NCCN clinical practice guidelines in oncology: Survivorship
[10]   Panel Testing Is Not a Panacea [J].
Axilbund, Jennifer E. .
JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (13) :1433-+
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