Direct sequence spread spectrum communication system simulation modeling of this problem, a simulation model of direct sequence spread spectrum communication system based on the Simulink, can reflect the dynamic process of the direct sequence spread spectrum communication system, and then the time domain waveform display, analysis of frequency spectrum analysis and system performance. Based on the overview of the spread spectrum communication theory and Simulink simulation, Simulink simulation of the DS-SS communication system, and the anti interference performance analysis, length and signal to noise ratio of the conclusion that the anti-jamming performance of the system and the spreading code sequences.