Immune escape strategies of Borrelia burgdorferi

被引：9
作者：
Aslam, Bilal [1 ]
Nisar, Muhammad Atif [1 ]
Khurshid, Mohsin [1 ,2 ]
Salamat, Muhammad Khalid Farooq [3 ]
机构：
[1] Govt Coll Univ, Dept Microbiol, Faisalabad, Pakistan
[2] Govt Coll Univ, Directorate Med Sci, Coll Allied Hlth Profess, Faisalabad, Pakistan
[3] Univ Edinburgh, Roslin Inst, Neurobiol Div, Easter Bush EH25 9RG, Midlothian, Scotland
来源：
FUTURE MICROBIOLOGY | 2017年 / 12卷 / 13期
关键词：
Borrelia burgdorferi; immune evasion; spirochete; LYME-DISEASE SPIROCHETE; INHIBITOR FACTOR-H; PERIPHERAL-BLOOD FIBROCYTES; SERUM-RESISTANT STRAINS; ENZOOTIC LIFE-CYCLE; SURFACE-PROTEIN; SENSU-LATO; MAMMALIAN HOST; ANTIGENIC VARIATION; GENETIC-VARIATION;
D O I：
10.2217/fmb-2017-0013
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The borrelial resurge demonstrates that Borrelia burgdorferi is a persistent health problem. This spirochete is responsible for a global public health concern called Lyme disease. B. burgdorferi faces diverse environmental conditions of its vector and host during its life cycle. To circumvent the host immune system is a prominent feature of B. burgdorferi. To date, numerous studies have reported on the various mechanisms used by this pathogen to evade the host defense mechanisms. This current review attempts to consolidate this information to describe the immunological and molecular methods used by B. burgdorferi for its survival.
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收藏
页码：1219 / 1237
页数：19
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