Electrochemical detection of single E. coli bacteria labeled with silver nanoparticles

被引：99
作者：
Sepunaru, Lior [1 ]
Tschulik, Kristina [1 ]
Batchelor-McAuley, Christopher [1 ]
Gavish, Rachel [2 ]
Compton, Richard G. [1 ]
机构：
[1] Univ Oxford, Dept Chem, Phys & Theoret Chem Lab, Oxford OX1 3QZ, England
[2] Schneider Childrens Med Ctr Israel, Dept Pediat C, IL-49202 Petah Tiqwa, Israel
来源：
BIOMATERIALS SCIENCE | 2015年 / 3卷 / 06期
基金：
欧洲研究理事会;
关键词：
CELL;
D O I：
10.1039/c5bm00114e
中图分类号：
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号：
0805 ; 080501 ; 080502 ;
摘要：
A proof-of-concept for the electrochemical detection of single Escherichia coli bacteria decorated with silver nanoparticles is reported. Impacts of bacteria with an electrode - held at a suitably oxidizing potential - lead to an accompanying burst of current with each collision event. The frequency of impacts scales with the concentration of bacteria and the charge indicates the extent of decoration.
引用
收藏
页码：816 / 820
页数：5
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