Limitations to carbon 13-labeled urea breath testing for Helicobacter pylori in infants

被引：68

作者：

Imrie, C

Rowland, M

Bourke, B

Drumm, B

机构：

[1] Our Ladys Hosp Sick Children, Childrens Res Ctr, Dublin 12, Ireland

[2] Univ Coll Dublin, Dept Paediat, Conway Inst Mol & Biomed Res, Dublin 2, Ireland

来源：

JOURNAL OF PEDIATRICS | 2001年 / 139卷 / 05期

基金：

英国惠康基金;

关键词：

D O I：

10.1067/mpd.2001.118398

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

We determined the validity of the carbon 13-labeled urea breath test in young children. We found that although the C-13-labeled urea breath test had a specificity greater than 90%, borderline or false positive results occurred more frequently in children younger than 2 years compared with older children. False positive results may be caused by oral-urease-producing organisms because direct intragastric administration of C-13 urea reduced the excess delta (CO2)-C-13. Care is urged in interpreting one positive C-13-Iabeled urea breath test in children younger than 2 years.

引用

收藏

页码：734 / 737

页数：4

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