Advances and applications of induced pluripotent stem cells

被引：0
|
作者：
Pietronave, Stefano [1 ]
Prat, Maria [1 ,2 ]
机构：
[1] Univ Piemonte Orientale, Dept Hlth Sci, Histol Lab, I-28100 Novara, Italy
[2] Ctr Biotecnol Ric Med Applicata BRMA, I-28100 Novara, Italy
来源：
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY | 2012年 / 90卷 / 03期
关键词：
iPS; retrovirus; regenerative medicine; drug discovery; HUMAN FIBROBLASTS; EPIGENETIC MEMORY; OPEN CHROMATIN; SOMATIC-CELLS; BLOOD-CELLS; GENERATION; MOUSE; EFFICIENT; EXPRESSION; INDUCTION;
D O I：
10.1139/Y11-125
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Direct reprogramming of somatic cells into pluripotent cells is an emerging technology for creating patient-specific cells, and potentially opens new scenarios in medical and pharmacological fields. From the discovery of Shinya Yamanaka, who first obtained pluripotent cells from fibroblasts by retrovirus-derived ectopic expression of defined embryonic transcription factors, new methods have been developed to generate safe induced pluripotent stem (iPS) cells without genomic manipulations. This review will focus on the recent advances in iPS technology and their application in pharmacology and medicine.
引用
收藏
页码：317 / 325
页数：9
相关论文
共 50 条
  • [31] Induced pluripotent stem cells are induced pluripotent stem cell-like cells
    Liting Song
    Emanuel Goldman
    The Journal of Biomedical Research, 2015, (01) : 1 - 2
  • [32] Induced Pluripotent Stem Cell-Derived Endothelial Cells Overview, Current Advances, Applications, and Future Directions
    Jang, Sae
    de l'Hortet, Alexandra Collin
    Soto-Gutierrez, Alejandro
    AMERICAN JOURNAL OF PATHOLOGY, 2019, 189 (03): : 502 - 512
  • [33] Advances and Challenges on Cancer Cells Reprogramming Using Induced Pluripotent Stem Cells Technologies
    Dias Camara, Diana Aparecida
    Mambelli, Lisley Inata
    Porcacchia, Allan Saj
    Kerkis, Irina
    JOURNAL OF CANCER, 2016, 7 (15): : 2296 - 2303
  • [34] Advances in the differentiation of pluripotent stem cells into vascular cells
    Jiao, Yi-Chang
    Wang, Ying-Xin
    Liu, Wen-Zhu
    Xu, Jing-Wen
    Zhao, Yu-Ying
    Yan, Chuan-Zhu
    Liu, Fu-Chen
    WORLD JOURNAL OF STEM CELLS, 2024, 16 (02): : 137 - 150
  • [35] Advances in Induced Pluripotent Stem Cell Technologies
    Pal, Rajarshi
    Rao, Mahendra
    Vemuri, Mohan C.
    Verma, Paul
    Dinnyes, Andras
    STEM CELLS INTERNATIONAL, 2012, 2012
  • [36] Induced pluripotent stem cells
    Shevchenko, A. I.
    Medvedev, S. P.
    Mazurok, N. A.
    Zakian, S. M.
    RUSSIAN JOURNAL OF GENETICS, 2009, 45 (02) : 139 - 146
  • [37] Induced pluripotent stem cells
    Bhowmik, Siddhartha
    Li Yong
    CHINESE MEDICAL JOURNAL, 2011, 124 (12) : 1897 - 1900
  • [38] Induced pluripotent stem cells
    Lisker-Y, Ruben
    REVISTA DE INVESTIGACION CLINICA-CLINICAL AND TRANSLATIONAL INVESTIGATION, 2010, 62 (05): : 396 - 397
  • [39] INDUCED PLURIPOTENT STEM CELLS
    Zaehres, Holm
    Kim, Jeong Beom
    Schoeler, Hans R.
    GUIDE TO TECHNIQUES IN MOUSE DEVELOPMENT, PT A: MICE, EMBRYOS, AND CELLS, 2ND EDITION, 2010, 476 : 309 - 325
  • [40] Induced pluripotent stem cells
    Siddhartha Bhowmik
    中华医学杂志（英文版）, 2011, (12) : 1897 - 1900
12345