Efficient and Selective Hydrosilylation of Carbonyl Compounds Catalyzed by Iron Acetate and N-Hydroxyethylimidazolium Salts

被引：62
作者：
Buitrago, Elina [1 ]
Tinnis, Fredrik [1 ]
Adolfsson, Hans [1 ]
机构：
[1] Stockholm Univ, Dept Organ Chem, Arrhenius Lab, SE-10691 Stockholm, Sweden
来源：
ADVANCED SYNTHESIS & CATALYSIS | 2012年 / 354卷 / 01期
基金：
瑞典研究理事会;
关键词：
aldehydes; carbenes; hydrosilylation; iron; ketones; ASYMMETRIC TRANSFER HYDROGENATION; HETEROCYCLIC-CARBENE COMPLEXES; ENANTIOSELECTIVE HYDROSILYLATION; KETONE HYDROSILYLATION; LIGANDS; COPPER; REDUCTION; METAL; NHC; POLYMETHYLHYDROSILOXANE;
D O I：
10.1002/adsc.201100606
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Aromatic aldehydes, along with aryl alkyl, heteroaryl alkyl, and dialkyl ketones were efficiently reduced to their corresponding primary and secondary alcohols, respectively, in high yields, using the commercially available and inexpensive polymeric silane, polymethylhydrosiloxane (PMHS), as reducing agent. The reaction is catalyzed by in situ generated iron complexes containing hydroxyethyl-functionalized NHC ligands. Turnover frequencies up to 600 h-1 were obtained.
引用
收藏
页码：217 / 222
页数：6
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