Precision medicine beyond medical oncology: using molecular analysis to guide treatments of colorectal neoplasia

被引:4
作者
Molloy, Mark P. [1 ]
Engel, Alexander [2 ]
机构
[1] Univ Sydney, Kolling Inst, Lawrence Penn Chair Bowel Canc Res, St Leonards, NSW, Australia
[2] Royal North Shore Hosp, Colorectal Surg, Sydney, NSW, Australia
关键词
Adenoma; colorectal cancer; genomics; polyps; precision medicine; LYMPH-NODE METASTASIS; CANCER; RISK; CARCINOMA; BIOMARKER; SIGNATURE; ASPIRIN;
D O I
10.1080/17474124.2018.1535897
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
引用
收藏
页码:1179 / 1181
页数:3
相关论文
共 22 条
  • [1] Systematic review: Gut microbiota in fecal samples and detection of colorectal neoplasms
    Amitay, Efrat L.
    Krilaviciute, Agne
    Brenner, Hermann
    [J]. GUT MICROBES, 2018, 9 (04) : 293 - 307
  • [2] [Anonymous], 2011, PREC MED BUILD KNOWL
  • [3] Expanded RAS: Refining the Patient Population
    Atreya, Chloe E.
    Corcoran, Ryan B.
    Kopetz, Scott
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2015, 33 (07) : 682 - 685
  • [4] Aspirin and the risk of colorectal cancer in relation to the expression of COX-2
    Chan, Andrew T.
    Ogino, Shuji
    Fuchs, Charles S.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2007, 356 (21) : 2131 - 2142
  • [5] Acquired somatic TP53 or PIK3CA mutations are potential predictors of when polyps evolve into colorectal cancer
    Chang, Pi-Yueh
    Chen, Jinn-Shiun
    Chang, Shih-Cheng
    Wang, Mei-Chia
    Chang, Nai-Chung
    Wen, Ying-Hao
    Tsai, Wen-Sy
    Liu, Wei-Hsiu
    Liu, Hsiu-Ling
    Lu, Jang-Jih
    [J]. ONCOTARGET, 2017, 8 (42) : 72352 - 72362
  • [6] Molecular characterization of colorectal adenomas with and without malignancy reveals distinguishing genome, transcriptome and methylome alterations
    Druliner, Brooke R.
    Wang, Panwen
    Bae, Taejeong
    Baheti, Saurabh
    Slettedahl, Seth
    Mahoney, Douglas
    Vasmatzis, Nikolaos
    Xu, Hang
    Kim, Minsoo
    Bockol, Matthew
    O'Brien, Daniel
    Grill, Diane
    Warner, Nathaniel
    Munoz-Gomez, Miguel
    Kossick, Kimberlee
    Johnson, Ruth
    Mouchli, Mohamad
    Felmlee-Devine, Donna
    Washechek-Aletto, Jill
    Smyrk, Thomas
    Oberg, Ann
    Wang, Junwen
    Chia, Nicholas
    Abyzov, Alexej
    Ablquist, David
    Boardman, Lisa A.
    [J]. SCIENTIFIC REPORTS, 2018, 8
  • [7] Colorectal Cancer with Residual Polyp of Origin: A Model of Malignant Transformation
    Druliner, Brooke R.
    Rashtak, Shahrooz
    Ruan, Xiaoyang
    Bae, Taejeong
    Vasmatzis, Nikolaos
    O'Brien, Daniel
    Johnson, Ruth
    Felmlee-Devine, Donna
    Washechek-Aletto, Jill
    Basu, Nivedita
    Liu, Hongfang
    Smyrk, Thomas
    Abyzov, Alexej
    Boardman, Lisa A.
    [J]. TRANSLATIONAL ONCOLOGY, 2016, 9 (04): : 280 - 286
  • [8] Gut microbiome development along the colorectal adenoma-carcinoma sequence
    Feng, Qiang
    Liang, Suisha
    Jia, Huijue
    Stadlmayr, Andreas
    Tang, Longqing
    Lan, Zhou
    Zhang, Dongya
    Xia, Huihua
    Xu, Xiaoying
    Jie, Zhuye
    Su, Lili
    Li, Xiaoping
    Li, Xin
    Li, Junhua
    Xiao, Liang
    Huber-Schoenauer, Ursula
    Niederseer, David
    Xu, Xun
    Al-Aama, Jumana Yousuf
    Yang, Huanming
    Wang, Jian
    Kristiansen, Karsten
    Arumugam, Manimozhiyan
    Tilg, Herbert
    Datz, Christian
    Wang, Jun
    [J]. NATURE COMMUNICATIONS, 2015, 6
  • [9] Generation and external validation of a tumor-derived 5-gene prognostic signature for recurrence of lymph node-negative, invasive colorectal carcinoma
    Lenehan, Peter F.
    Boardman, Lisa A.
    Riegert-Johnson, Douglas
    De Petris, Giovanni
    Fry, David W.
    Ohrnberger, Jeanne
    Heyman, Eugene R.
    Gerard, Brigitte
    Almal, Arpit A.
    Worzel, William P.
    [J]. CANCER, 2012, 118 (21) : 5234 - 5244
  • [10] Aspirin Use, Tumor PIK3CA Mutation, and Colorectal-Cancer Survival
    Liao, Xiaoyun
    Lochhead, Paul
    Nishihara, Reiko
    Morikawa, Teppei
    Kuchiba, Aya
    Yamauchi, Mai
    Imamura, Yu
    Qian, Zhi Rong
    Baba, Yoshifumi
    Shima, Kaori
    Sun, Ruifang
    Nosho, Katsuhiko
    Meyerhardt, Jeffrey A.
    Giovannucci, Edward
    Fuchs, Charles S.
    Chan, Andrew T.
    Ogino, Shuji
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2012, 367 (17) : 1596 - 1606