From birth to death: The complex lives of eukaryotic mRNAs

被引：783

作者：

Moore, MJ ^{[1
]}

机构：

[1] Brandeis Univ, Howard Hughes Med Inst, Dept Biochem, Waltham, MA 02454 USA

来源：

SCIENCE | 2005年 / 309卷 / 5740期

关键词：

D O I：

10.1126/science.1111443

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Recent work indicates that the posttranscriptional control of eukaryotic gene expression is much more elaborate and extensive than previously thought, with essentially every step of messenger RNA (mRNA) metabolism being subject to regulation in an mRNA-specific manner. Thus, a comprehensive understanding of eukaryotic gene expression requires an appreciation for how the lives of mRNAs are influenced by a wide array of diverse regulatory mechanisms.

引用

页码：1514 / 1518

页数：5

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