Checkpoint Immunotherapy : Picking a Winner

被引：8
作者：
Teng, Michele W. L. [1 ]
Khanna, Rajiv [1 ]
Smyth, Mark J. [1 ]
机构：
[1] QIMR Berghofer Med Res Inst, 300 Herston Rd, Herston, Qld 4006, Australia
来源：
CANCER DISCOVERY | 2016年 / 6卷 / 08期
关键词：
TUMOR MICROENVIRONMENT; IMMUNE-RESPONSES; NEOANTIGENS; CANCER; MELANOMA; BLOCKADE;
D O I：
10.1158/2159-8290.CD-16-0694
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Robust biomarkers of response that predict which patients will or will not respond to immune checkpoint blockade need to be identified. New data suggest that the presence of an adaptive immune signature in the tumor biopsies of patients with melanoma early on therapy compared to pretreatment can identify responders from nonresponders. (C) 2016 AACR.
引用
收藏
页码：818 / 820
页数：3
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