Changes in Energy Expenditure with Weight Gain and Weight Loss in Humans

被引：153
作者：
Mueller, Manfred J. [1 ]
Enderle, Janna [1 ]
Bosy-Westphal, Anja [2 ]
机构：
[1] Univ Kiel, Inst Human Nutr & Food Sci, Fac Agr & Nutr Sci, Dusternbrooker Weg 17, D-24105 Kiel, Germany
[2] Univ Hohenheim, Inst Nutr Med, Stuttgart, Germany
来源：
CURRENT OBESITY REPORTS | 2016年 / 5卷 / 04期
关键词：
Energy expenditure; Resting energy expenditure (REE); Total energy expenditure (TEE); Diet-induced thermogenesis (DIT); Activity-related energy expenditure (AEE); Exercise activity thermogenesis (EAT); Non-exercise activity thermogenesis (NEAT); Energy balance; Metabolic efficiency; Body composition; Fat mass; Fat-free mass (FFM); Total body water (TBW); Obesity; Leptin; Insulin; Thyroid hormones; SNS activity; Adaptive thermogenesis (AT); Caloric restriction; Overfeeding; Weight loss; Weight maintenance; BODY-COMPOSITION CHANGES; ADAPTIVE THERMOGENESIS; METABOLIC ADAPTATION; CALORIC RESTRICTION; RECOMBINANT LEPTIN; OBESE ADULTS; YOUNG MEN; OVERWEIGHT; MAINTENANCE; EXERCISE;
D O I：
10.1007/s13679-016-0237-4
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Metabolic adaptation to weight changes relates to body weight control, obesity and malnutrition. Adaptive thermogenesis (AT) refers to changes in resting and non-resting energy expenditure (REE and nREE) which are independent from changes in fat-free mass (FFM) and FFM composition. AT differs in response to changes in energy balance. With negative energy balance, AT is directed towards energy sparing. It relates to a reset of biological defence of body weight and mainly refers to REE. After weight loss, AT of nREE adds to weight maintenance. During overfeeding, energy dissipation is explained by AT of the nREE component only. As to body weight regulation during weight loss, AT relates to two different set points with a settling between them. During early weight loss, the first set is related to depleted glycogen stores associated with the fall in insulin secretion where AT adds to meet brain's energy needs. During maintenance of reduced weight, the second set is related to low leptin levels keeping energy expenditure low to prevent triglyceride stores getting too low which is a risk for some basic biological functions (e.g., reproduction). Innovative topics of AT in humans are on its definition and assessment, its dynamics related to weight loss and its constitutional and neuro-endocrine determinants.
引用
收藏
页码：413 / 423
页数：11
相关论文
共 76 条
[1]   A STUDY OF THE RELATIONSHIP BETWEEN THERMOGENESIS AND THYROID-HORMONES [J].
ACHESON, KJ ;
BURGER, AG .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1980, 51 (01) :84-89
[2]   Effects of weight gain induced by controlled overfeeding on physical activity [J].
Apolzan, John W. ;
Bray, George A. ;
Smith, Steven R. ;
de Jonge, Lilian ;
Rood, Jennifer ;
Han, Hongmei ;
Redman, Leanne M. ;
Martin, Corby K. .
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2014, 307 (11) :E1030-E1037
[3]   Intra- and interindividual variability of resting energy expenditure in healthy male subjects -: biological and methodological variability of resting energy expenditure [J].
Bader, N ;
Bosy-Westphal, A ;
Dilba, B ;
Müller, MJ .
BRITISH JOURNAL OF NUTRITION, 2005, 94 (05) :843-849
[4]   Effect of weight loss and regain on adipose tissue distribution, composition of lean mass and resting energy expenditure in young overweight and obese adults [J].
Bosy-Westphal, A. ;
Schautz, B. ;
Lagerpusch, M. ;
Pourhassan, M. ;
Braun, W. ;
Goele, K. ;
Heller, M. ;
Glueer, C-C ;
Mueller, M. J. .
INTERNATIONAL JOURNAL OF OBESITY, 2013, 37 (10) :1371-1377
[5]   Issues in characterizing resting energy expenditure in obesity and after weight loss [J].
Bosy-Westphal, Anja ;
Braun, Wiebke ;
Schautz, Britta ;
Mueller, Manfred J. .
FRONTIERS IN PHYSIOLOGY, 2013, 4
[6]   Contribution of individual organ mass loss to weight loss-associated decline in resting energy expenditure [J].
Bosy-Westphal, Anja ;
Kossel, Elke ;
Goele, Kristin ;
Later, Wiebke ;
Hitze, Britta ;
Settler, Uta ;
Heller, Martin ;
Glueer, Claus-Christian ;
Heymsfield, Steven B. ;
Mueller, Manfred J. .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2009, 90 (04) :993-1001
[7]   Grade of adiposity affects the impact of fat mass on resting energy expenditure in women [J].
Bosy-Westphal, Anja ;
Mueller, Manfred J. ;
Boschmann, Michael ;
Klaus, Susanne ;
Kreymann, Georg ;
Luehrmann, Petra M. ;
Neuhaeuser-Berthold, Monika ;
Noack, Rudolf ;
Pirke, Karl M. ;
Platte, Petra ;
Selberg, Oliver ;
Steiniger, Jochen .
BRITISH JOURNAL OF NUTRITION, 2009, 101 (04) :474-477
[8]   Effect of protein overfeeding on energy expenditure measured in a metabolic chamber [J].
Bray, George A. ;
Redman, Leanne M. ;
de Jonge, Lilian ;
Covington, Jeffrey ;
Rood, Jennifer ;
Brock, Courtney ;
Mancuso, Susan ;
Martin, Corby K. ;
Smith, Steven R. .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2015, 101 (03) :496-505
[9]   Changes in Resting Energy Expenditure in Relation to Body Weight and Composition Following Gastric Restriction: A Systematic Review [J].
Browning, Matthew G. ;
Franco, Robert L. ;
Cyrus, John C. ;
Celi, Francesco ;
Evans, Ronald K. .
OBESITY SURGERY, 2016, 26 (07) :1607-1615
[10]   Energetic Adaptations Persist After Bariatric Surgery in Severely Obese Adolescents [J].
Butte, Nancy F. ;
Brandt, Mary L. ;
Wong, William W. ;
Liu, Yan ;
Mehta, Nitesh R. ;
Wilson, Theresa A. ;
Adolph, Anne L. ;
Puyau, Maurice R. ;
Vohra, Firoz A. ;
Shypailo, Roman J. ;
Zakeri, Issa F. .
OBESITY, 2015, 23 (03) :591-601
12345678