Methamphetamine - properties and analytical methods of enantiomer determination

被引：51

作者：

Jirovsky, D

Lemr, K

Sevcik, J

Smysl, B

Stransky, Z

机构：

[1] Palacky Univ, Lab Bioanalyt Res, Olomouc 77146, Czech Republic

[2] Palacky Univ, Fac Sci, Dept Analyt Chem, Olomouc 77146, Czech Republic

[3] Palacky Univ, Fac Med, Inst Forens Med & Med Law, Olomouc 377509, Czech Republic

来源：

FORENSIC SCIENCE INTERNATIONAL | 1998年 / 96卷 / 01期

关键词：

methamphetamine; enantiomer;

D O I：

10.1016/S0379-0738(98)00104-2

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

Methamphetamine is one of the most frequently abused drugs of today. Due to its stereogenic center, it can exist as single enantiomer. Like many other chiral compounds, methamamphetamine enantiomers exhibit different pharmacological effects on living organisms. For this reason, it is necessary to develop enantioselective and sufficiently sensitive methods of determination. This review focuses on methamphetamine with an accent on analytical chemistry and especially on chiral separations of this toxicologically important compound. (C) 1998 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：61 / 70

页数：10

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