Burden of Undiagnosed Hypertension in Sub-Saharan Africa A Systematic Review and Meta-Analysis

被引:445
作者
Ataklte, Feven [1 ]
Erqou, Sebhat [2 ,3 ]
Kaptoge, Stephen [4 ]
Taye, Betiglu [5 ]
Echouffo-Tcheugui, Justin B. [6 ,7 ]
Kengne, Andre P. [8 ,9 ,10 ,11 ,12 ]
机构
[1] Kings Coll London, Dept Med, London, England
[2] Weill Cornell Med Coll, Dept Med, New York, NY 10065 USA
[3] Veteran Affairs Pittsburgh Hlth Care Syst, Pittsburgh, PA USA
[4] Univ Cambridge, Dept Publ Hlth & Primary Care, Cambridge, England
[5] Jama Med Ctr, Dept Med, New York, NY USA
[6] Emory Univ, Rollins Sch Publ Hlth, Hubert Dept Publ Hlth, Atlanta, GA 30322 USA
[7] MedStar Hlth, Baltimore, MD USA
[8] South African Med Res Council, Cape Town, South Africa
[9] Univ Cape Town, ZA-7925 Cape Town, South Africa
[10] George Inst Global Hlth, Sydney, NSW, Australia
[11] Univ Med Ctr Utrecht, Julius Ctr Hlth Sci, Utrecht, Netherlands
[12] Univ Med Ctr Utrecht, Primary Care, Utrecht, Netherlands
关键词
Africa south of the Sahara; cardiovascular diseases; hypertension; review; CARDIOVASCULAR RISK-FACTORS; BLOOD-PRESSURE; INCOME COUNTRIES; PREVALENCE; URBAN; POPULATION; AWARENESS; DISEASE; MANAGEMENT; ADULTS;
D O I
10.1161/HYPERTENSIONAHA.114.04394
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
The burden of hypertension in Sub-Saharan Africa has been increasing over the past few decades. However, a large proportion of the population with hypertension remains undiagnosed, untreated, or inadequately treated, contributing to the rising burden of cardiovascular disease in the region. We conducted a systematic review and meta-analysis to assess the recent burden of hypertension in Sub-Saharan Africa, based on studies published between 2000 and 2013. We pooled data from 33 surveys involving over 110 414 participants of mean age 40 years. Hypertension prevalence varied widely across the studies (range 15%-70%), partly because of differences in participant mean ages (31-76 years). The predicted prevalence of hypertension at mean participant ages of 30, 40, 50, and 60 years were 16%, 26%, 35%, and 44%, respectively, with a pooled prevalence of 30% (95% confidence interval, 27%-34%). Of those with hypertension, only between 7% and 56% (pooled prevalence: 27%; 95% confidence interval, 23%-31%) were aware of their hypertensive status before the surveys. Overall, 18% (95% confidence interval, 14%-22%) of individuals with hypertension were receiving treatment across the studies, and only 7% (95% confidence interval, 5%-8%) had controlled blood pressure. This review found a high prevalence of hypertension, as well as low percentage of hypertension awareness, treatment, and control in Sub-Saharan Africa, highlighting the need for implementation of timely and appropriate strategies for diagnosis, control, and prevention.
引用
收藏
页码:291 / U115
页数:32
相关论文
共 53 条
[1]   Hypertension in sub-Saharan Africa - A systematic review [J].
Addo, Juliet ;
Smeeth, Liam ;
Leon, David A. .
HYPERTENSION, 2007, 50 (06) :1012-1018
[2]   Hypertensive Target Organ Damage in Ghanaian Civil Servants with Hypertension [J].
Addo, Juliet ;
Smeeth, Liam ;
Leon, David A. .
PLOS ONE, 2009, 4 (08)
[3]   Rural and urban differences in blood pressure and hypertension in Ghana, West Africa [J].
Agyemang, Charles .
PUBLIC HEALTH, 2006, 120 (06) :525-533
[4]  
[Anonymous], World Health Statistics 2012
[5]  
[Anonymous], 2013, A global brief on hypertension: silent killer, global public health Crisis
[6]   Prevalence of cardiovascular risk factors in an urban area of Togo: a WHO STEPS-wise approach in Lome, Togo [J].
Baragou, S. ;
Djibril, M. ;
Atta, B. ;
Damorou, F. ;
Pio, M. ;
Balogou, A. .
CARDIOVASCULAR JOURNAL OF AFRICA, 2012, 23 (06) :308-311
[7]   Meta-analysis of prevalence [J].
Barendregt, Jan J. ;
Doi, Suhail A. ;
Lee, Yong Yi ;
Norman, Rosana E. ;
Vos, Theo .
JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH, 2013, 67 (11) :974-978
[8]   Social Epidemiology of Hypertension in Middle-Income Countries: Determinants of Prevalence, Diagnosis, Treatment, and Control in the WHO SAGE Study [J].
Basu, Sanjay ;
Millett, Christopher .
HYPERTENSION, 2013, 62 (01) :18-26
[9]   Distribution of blood pressure, body mass index and smoking habits in the urban population of Dar es Salaam, Tanzania, and associations with socioeconomic status [J].
Bovet, P ;
Ross, AG ;
Gervasoni, JP ;
Mkamba, M ;
Mtasiwa, DM ;
Lengeler, C ;
Whiting, D ;
Paccaud, F .
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2002, 31 (01) :240-247
[10]   Prevalence of cardiovascular risk factors in a middle-income country and estimated cost of a treatment strategy [J].
Bovet, P ;
Shamlaye, C ;
Gabriel, A ;
Riesen, W ;
Paccaud, F .
BMC PUBLIC HEALTH, 2006, 6 (1)