Juvenile Myelomonocytic Leukemia in a Premature Neonate Mimicking Neonatal Sepsis

被引：4

作者：

Lee, Ming-Luen ^{[1
,2
]}

Yen, Hsiu-Ju ^{[1
,2
]}

Chen, Shu-Jen ^{[1
,2
]}

Hung, Giun-Yi ^{[1
,2
]}

Tsao, Pei-Chen ^{[1
,2
,3
]}

Soong, Wen-Jue ^{[1
,2
,3
]}

机构：

[1] Taipei Vet Gen Hosp, Dept Pediat, 201 Shih Pai Rd,Sect 2, Taipei 11217, Taiwan

[2] Natl Yang Ming Univ, Sch Med, Taipei 112, Taiwan

[3] Natl Yang Ming Univ, Inst Emergency & Crit Care Med, Taipei 112, Taiwan

来源：

PEDIATRICS AND NEONATOLOGY | 2016年 / 57卷 / 02期

关键词：

juvenile myelomonocytic leukemia; newborn; premature neonate; NOONAN-SYNDROME; DISORDERS; CHILDHOOD; PTPN11;

D O I：

10.1016/j.pedneo.2013.06.009

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Juvenile myelomonocytic leukemia (JMML) is a rare hematologic malignancy in children. Its presentations include anemia, thrombocytopenia, monocytosis, skin rash, marked hepatomegaly, and/or splenomegaly. Fever and respiratory involvement are common. Here, we report a case of a premature neonate with initial symptoms of respiratory distress. She gradually developed clinical manifestations of JMML that mimicked neonatal sepsis. Three weeks after birth, JMML was diagnosed. This is the first reported case of JMML presenting in a premature infant in Taiwan. Copyright (C) 2013, Taiwan Pediatric Association. Published by Elsevier Taiwan LLC. All rights reserved.

引用

页码：149 / 152

页数：4

共 14 条

[1] Juvenile myelomonocytic leukemia [J].