Drug Delivery: From a Contact Lens to the Anterior Chamber

被引:0
|
作者
Ferreira, J. A. [1 ]
de Oliveira, P. [1 ]
Silva, P. [2 ]
Murta, J. N. [3 ]
机构
[1] Univ Coimbra, CMUC, Dept Math, P-3001454 Coimbra, Portugal
[2] ISEC, Dept Math & Phys, P-3030199 Coimbra, Portugal
[3] Univ Coimbra, Dept Ophthalmol, Fac Med, P-3001454 Coimbra, Portugal
来源
CMES-COMPUTER MODELING IN ENGINEERING & SCIENCES | 2011年 / 71卷 / 01期
关键词
Ophthalmic contact lens; nanoparticles; polymeric matrix; cornea; anterior chamber; diffusion; EXTENDED DELIVERY; OPHTHALMIC DRUGS; RELEASE; HYDROGEL;
D O I
暂无
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Mathematical models to describe drug concentration profiles of topically administered drug in the anterior chamber aqueous humor have been proposed by several authors. The aim of this paper is to present a mathematical model to predict the drug concentration in the anterior chamber when a therapeutical contact lens with the drug entrapped in nanoparticles is used.
引用
收藏
页码:1 / 14
页数:14
相关论文
共 50 条
  • [1] Contact Lens Drug Delivery
    不详
    ATLA-ALTERNATIVES TO LABORATORY ANIMALS, 2016, 44 (06): : 517 - 517
  • [2] Migration of an intravitreal dexamethasone implant into the anterior chamber in contact with an anterior chamber intraocular lens
    Callet, M.
    Sampo, M.
    Hugo, J.
    Speybrouck-Grebert, A.
    Hoffart, L.
    JOURNAL FRANCAIS D OPHTALMOLOGIE, 2018, 41 (03): : E107 - E109
  • [3] Mechanistic modeling of ophthalmic drug delivery to the anterior chamber by eye drops and contact lenses
    Gause, Samuel
    Hsu, Kuan-Hui
    Shafor, Chancellor
    Dixon, Phillip
    Powell, Kristin Conrad
    Chauhan, Anuj
    ADVANCES IN COLLOID AND INTERFACE SCIENCE, 2016, 233 : 139 - 154
  • [4] Contact lens measures drug concentration in the anterior eye
    Overton, G
    LASER FOCUS WORLD, 2005, 41 (12): : 13 - 14
  • [5] Delivery of ionic molecules to anterior chamber by iontophoretic contact lenses
    Christopher, Keith
    Chauhan, Anuj
    EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2019, 140 : 40 - 49
  • [6] Drug Delivery by Contact Lens in Spontaneously Glaucomatous Dogs
    Peng, Cheng-Chun
    Ben-Shlomo, Anna
    Mackay, Edward O.
    Plummer, Caryn E.
    Chauhan, Anuj
    CURRENT EYE RESEARCH, 2012, 37 (03) : 204 - 211
  • [7] Development of a novel contact lens for drug delivery purposes
    Fuchsluger, Thomas
    ACTA OPHTHALMOLOGICA, 2024, 102
  • [8] A comprehensive review on contact lens for ophthalmic drug delivery
    Xu, Jiawen
    Xue, Yingyan
    Hu, Gaoyong
    Lin, Tianyu
    Gou, Jingxin
    Yin, Tian
    He, Haibing
    Zhang, Yu
    Tang, Xing
    JOURNAL OF CONTROLLED RELEASE, 2018, 281 : 97 - 118
  • [9] From Vision Correction to Drug Delivery: Unraveling the Potential of Therapeutic Contact Lens
    Saini, Ankush
    Sharma, Mohit
    Singh, Indu
    Swami, Rajan
    CURRENT DRUG DELIVERY, 2025, 22 (02) : 140 - 159
  • [10] DISLOCATION OF LENS INTO ANTERIOR CHAMBER
    LEWIS, PM
    AMERICAN JOURNAL OF OPHTHALMOLOGY, 1946, 29 (03) : 348 - 348