Retinal involvement in dementia with Lewy bodies: A clue to hallucinations?

被引：45
|
作者：
Maurage, CA
Ruchoux, MM
de Vos, R
Surguchov, A
Destree, A
机构：
[1] Ctr Hosp Reg & Univ Lille, R Salengro Hosp, Dept Neuropathol, MENRT,EA 2691, F-59037 Lille, France
[2] Dept Pathol E Netherlands, Enschede, Netherlands
[3] VAMC, Neurobiol Res Lab, Kansas City, KS USA
[4] Univ Kansas, Med Ctr, Kansas City, KS 66103 USA
[5] Ctr Hosp Reg & Univ Lille, R Salengro Hosp, Dept Neurol, F-59037 Lille, France
[6] Ctr Hosp Reg & Univ Lille, R Salengro Hosp, EA Menrit 2683, F-59037 Lille, France
来源：
ANNALS OF NEUROLOGY | 2003年 / 54卷 / 04期
关键词：
D O I：
10.1002/ana.10730
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Visual hallucinations are a core feature of dementia with Lewy bodies. Their pathophysiology is not well understood, because neither clinical nor histological data have shown their basic mechanisms. Here, we report the presence of pale inclusions in the outer plexiform layer of the retina in a patient with dementia with Lewy bodies. These inclusions are related to cytoskeletal disorganization of the cones at ultrastructural level and modifications of the immunohistochemical pattern of distribution of synucleins in the retina. These modifications may participate in the visual impairment in dementia with Lewy bodies.
引用
收藏
页码：542 / 547
页数：6
相关论文
共 50 条
  • [21] Visual Hallucinations in Parkinson Disease and Dementia with Lewy Bodies: a review
    Regala, Joana
    Nobrega, Camila
    Reis, Joao
    INTERNATIONAL PSYCHOGERIATRICS, 2020, 32 : 139 - 139
  • [22] Visual Hallucinations and α-Synuclein Oligomers in Dementia with Lewy Bodies (DLB)
    Franke, L.
    Sekiya, H.
    Ferman, T.
    McLean, P.
    Dickson, D.
    MOVEMENT DISORDERS, 2024, 39 : S56 - S58
  • [23] Visual Hallucinations in Dementia with Lewy Bodies (II): Computational Aspects
    Tsukada, Hiromichi
    Fujii, Hiroshi
    Tsuda, Ichiro
    Aihara, Kazuyuki
    ADVANCES IN COGNITIVE NEURODYNAMICS (IV), 2015, : 589 - 595
  • [24] The brain metabolic signature of visual hallucinations in dementia with Lewy bodies
    Iaccarino, Leonardo
    Sala, Arianna
    Caminiti, Silvia Paola
    Santangelo, Roberto
    Iannaccone, Sandro
    Magnani, Giuseppe
    Perani, Daniela
    CORTEX, 2018, 108 : 13 - 24
  • [25] IMPAIRED COLOR DISCRIMINATION IS ASSOCIATED WITH HALLUCINATIONS IN DEMENTIA WITH LEWY BODIES
    Matar, Elie
    Phillips, Joseph R.
    Martens, Kaylena A. Ehgoetz
    Halliday, Glenda M.
    Lewis, Simon J. G.
    JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2019, 90 (E7):
  • [26] Visual Hallucinations in Dementia with Lewy Bodies (I): A Hodological View
    Fujii, Hiroshi
    Tsukada, Hiromichi
    Tsuda, Ichiro
    Aihara, Kazuyuki
    ADVANCES IN COGNITIVE NEURODYNAMICS (IV), 2015, : 441 - 445
  • [27] Change in perfusion, hallucinations and fluctuations in consciousness in dementia with Lewy bodies
    O'Brien, JT
    Firbank, MJ
    Mosimann, UP
    Burn, DJ
    McKeith, IG
    PSYCHIATRY RESEARCH-NEUROIMAGING, 2005, 139 (02) : 79 - 88
  • [28] Visual hallucinations in Alzheimer's disease: Possible involvement of low visual acuity and dementia with Lewy bodies
    Terao, T
    JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES, 2000, 12 (04) : 516 - 517
  • [29] Visual hallucinations in dementia with Lewy bodies transcranial magnetic stimulation study
    Taylor, John-Paul
    Firbank, Michael
    Barnett, Nicola
    Pearce, Sarah
    Livingstone, Anthea
    Mosimann, Urs
    Eyre, Janet
    McKeith, Ian G.
    O'Brien, John T.
    BRITISH JOURNAL OF PSYCHIATRY, 2011, 199 (06) : 492 - 500
  • [30] Patients characteristics with cholinesterase inhibitor resistant hallucinations in dementia with Lewy bodies
    Lebert, Florence
    Pasquier, Florence
    JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2007, 78 (12): : 1415 - 1416
12345