Reversibility of hepatitis B virus-induced liver cirrhosis after prolonged antiviral therapy

被引：2

作者：

Perez Roldan, Francisco ^{[1
]}

Vives Dominguez, Leopoldo

Gonzalez Carro, Pedro ^{[1
]}

Villafanez Garcia, Maria Concepcion ^{[2
]}

Fernandez Acenero, Maria Jesus ^{[3
]}

Cuesta Dominguez, Ruben ^{[4
]}

Aoufi Rabih, Sami ^{[1
]}

Ruiz Carrillo, Francisco ^{[1
]}

机构：

[1] Hosp Gen La Mancha Ctr, Secc Aparato Digest, Alcazar De San Juan, Spain

[2] Hosp Gen La Mancha Ctr, Serv Urgencias, Alcazar De San Juan, Spain

[3] Fdn Jimenez Diaz, Serv Anat Patol, E-28040 Madrid, Spain

[4] Hosp Gen La Mancha Ctr, Serv Anat Patol, Alcazar De San Juan, Spain

来源：

GASTROENTEROLOGIA Y HEPATOLOGIA | 2010年 / 33卷 / 07期

关键词：

Reversibility of liver; cirrhosis; Hepatitis B virus; Antiviral therapy; LAMIVUDINE; FIBROSIS; DISEASE; INFECTION; REVERSAL;

D O I：

10.1016/j.gastrohep.2010.04.007

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Reversibility of liver fibrosis or cirrhosis involves complete restoration of normal liver architecture. This phenomenon has been well documented in chronic liver diseases such as autoimmune hepatitis, biliary obstruction, hemochromatosis, nonalcoholic steatohepatitis, and viral hepatitis. There are very few reports of reversal of cirrhosis after antiviral therapy in patients with chronic hepatitis B virus (HBV) infection. We report a case of disappearance of HBV-induced liver cirrhosis after years of treatment with distinct antiviral drugs, documented by successive biopsy results. This disappearance was accompanied by normalization of platelet count, gammaglobulin titers, and radiologic findings. (C) 2010 Elsevier Espana, S.L. All rights reserved.

引用

页码：498 / 503

页数：6

共 50 条

[1] Antiviral Therapy in Patients with Hepatitis C Virus-Induced Cirrhosis
Bailly, Francois
Pradat, Pierre
Virlogeux, Victor
Zoulim, Fabien
DIGESTIVE DISEASES, 2015, 33 (04) : 613 - 623
[2] Reversibility of hepatitis B virus cirrhosis after therapy: who and why?
Bedossa, Pierre
LIVER INTERNATIONAL, 2015, 35 : 78 - 81
[3] Antiviral Therapy of Liver Cirrhosis Related to Hepatitis B Virus Infection
Lu, Lun-Gen
JOURNAL OF CLINICAL AND TRANSLATIONAL HEPATOLOGY, 2014, 2 (03) : 197 - 201
[4] Antiviral Therapy in Hepatitis B Virus-Associated Liver Cirrhosis
Boettler, Tobias
Thimme, Robert
DIGESTIVE DISEASES, 2015, 33 (04) : 608 - 612
[5] Antiviral Therapy in Decompensated Cirrhosis due to Hepatitis B Virus
Fu, Qingchun
Chen, Chengwei
GUT AND LIVER, 2011, 174 : 123 - 126
[6] Antiviral therapy delays esophageal variceal bleeding in hepatitis B virus-related cirrhosis
Li, Chang-Zheng
Cheng, Liu-Fang
Li, Qing-Shan
Wang, Zhi-Qiang
Yan, Jun-Hong
WORLD JOURNAL OF GASTROENTEROLOGY, 2013, 19 (40) : 6849 - 6856
[7] Antiviral therapy of decompensated hepatitis B virus-related cirrhosis
Chen Guang-cheng
Yu Tao
Huang Kai-hong
Chen Qi-kui
CHINESE MEDICAL JOURNAL, 2012, 125 (02) : 373 - 377
[8] Chronic hepatitis B with advanced fibrosis or cirrhosis: Impact of antiviral therapy
Arora, Gaurav
Keeffe, Emmet B.
REVIEWS IN GASTROENTEROLOGICAL DISORDERS, 2007, 7 (02) : 63 - 73
[9] Hepatitis B virus-related decompensated liver cirrhosis: Benefits of antiviral therapy
Peng, Cheng-Yuan
Chien, Rong-Nan
Liaw, Yun-Fan
JOURNAL OF HEPATOLOGY, 2012, 57 (02) : 442 - 450
[10] Reduction of liver stiffness by antiviral therapy in chronic hepatitis B
Osakabe, Keisuke
Ichino, Naohiro
Nishikawa, Toru
Sugiyama, Hiroko
Kato, Miho
Kitahara, Shiho
Hashimoto, Senju
Kawabe, Naoto
Harata, Masao
Nitta, Yoshifumi
Murao, Michihito
Nakano, Takuji
Shimazaki, Hiroaki
Arima, Yuko
Suzuki, Koji
Yoshioka, Kentaro
JOURNAL OF GASTROENTEROLOGY, 2011, 46 (11) : 1324 - 1334

← 1 2 3 4 5 →