The role of immune cells in atrial fibrillation

被引：66

作者：

Liu, Yaozhong ^{[1
]}

Shil, Qiman ^{[1
]}

Ma, Yingxu ^{[1
]}

Liu, Qiming ^{[1
]}

机构：

[1] Cent S Univ, Xiangya Hosp 2, Dept Cardiol, Changsha, Hunan, Peoples R China

来源：

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY | 2018年 / 123卷

关键词：

Immunity; Immune cells; Atrial fibrillation; Cytokine; Mechanism; TUMOR-NECROSIS-FACTOR; CORONARY-ARTERY-DISEASE; CHRONIC HEART-FAILURE; CARDIAC-ARRHYTHMIAS; MAST-CELLS; NEUTROPHIL/LYMPHOCYTE RATIO; MATRIX METALLOPROTEINASE-2; THERAPEUTIC IMPLICATIONS; ACETYLCHOLINE-RECEPTORS; INFLAMMASOME ACTIVATION;

D O I：

10.1016/j.yjmcc.2018.09.007

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Atrial fibrillation (AF) is the most common sustained arrhythmia, but its mechanisms are poorly understood. Recently, accumulating evidence indicates a link between immune response and AF, but the precise mechanism remains unclear. It should be noticed that the relationship between immune response and AF is complex. Whether immune response is a cause or a result of AF is unclear. As the functional unit of the immune system, immune cells may play a vital role in the immunological pathogenesis of AF. In this review, we briefly highlight the evidence on relationships between immune cells and AF, and discuss their potential roles in AF pathogenesis. We hope this review could provide new orientation and enlightenment for further research on AF mechanism.

引用

页码：198 / 208

页数：11

共 137 条

[1] Association of Met439Thr substitution in heat shock protein 70 gene with postoperative atrial fibrillation and serum HSP70 protein levels [J].

Afzal, Ali R. ;

Mandal, Kaushik ;

Nyamweya, Samuel ;

Foteinos, Georgios ;

Poloniecki, Jan ;

Camm, A. John ;

Jahangiri, Marjan ;

Xu, Qingbo .

CARDIOLOGY, 2008, 110 (01) :45-52

[2] The Clinical Profile and Pathophysiology of Atrial Fibrillation Relationships Among Clinical Features, Epidemiology, and Mechanisms [J].

Andrade, Jason ;

Khairy, Paul ;

Dobrev, Dobromir ;

Nattel, Stanley .

CIRCULATION RESEARCH, 2014, 114 (09) :1453-1468

[3] Inflammation as a risk factor for atrial fibrillation [J].

Aviles, RJ ;

Martin, DO ;

Apperson-Hansen, C ;

Houghtaling, PL ;

Rautaharju, P ;

Kronmal, RA ;

Tracy, RP ;

Van Wagoner, DR ;

Psaty, BM ;

Lauer, MS ;

Chung, MK .

CIRCULATION, 2003, 108 (24) :3006-3010

[4] Autoantibodies against M2-muscarinic acetylcholine receptors: new upstream targets in atrial fibrillation in patients with dilated cardiomyopathy [J].

Baba, A ;

Yoshikawa, T ;

Fukuda, Y ;

Sugiyama, T ;

Shimada, M ;

Akaishi, M ;

Tsuchimoto, K ;

Ogawa, S ;

Fu, M .

EUROPEAN HEART JOURNAL, 2004, 25 (13) :1108-1115

[5] Autoantibodies in atrial fibrillation: Actor, biomaker or bystander? [J].

Baba, Akiyasu ;

Fu, Michael .

AUTOIMMUNITY, 2008, 41 (06) :470-472

[6]

Baba Akiyasu, 2002, J Cardiol, V40, P217

[7] Prevalence and the clinical outcome of atrial fibrillation in patients with Autoimmune Rheumatic Disease [J].

Baek, Yong-Soo ;

Kim, Tae-Hoon ;

Uhm, Jae-Sun ;

Kim, Jong-Yun ;

Pak, Hui-Nam ;

Lee, Moon-Hyoung ;

Joung, Boyoung .

INTERNATIONAL JOURNAL OF CARDIOLOGY, 2016, 214 :4-9

[8] Na/K-ATPase-An Integral Player in the Adrenergic Fight-or-Flight Response [J].

Bers, Donald M. ;

Despa, Sanda .

TRENDS IN CARDIOVASCULAR MEDICINE, 2009, 19 (04) :111-118

[9] Is atrial fibrillation an inflammatory disorder? [J].

Boos, CJ ;

Anderson, RA ;

Lip, GYH .

EUROPEAN HEART JOURNAL, 2006, 27 (02) :136-149

[10] Prospective assessment of cytokine IL-15 activity in patients with refractory atrial fibrillation episodes [J].

Borowiec, Anna ;

Kontny, Ewa ;

Smolis-Bak, Edyta ;

Kowalik, Ilona ;

Majos, Ewa ;

Zalucka, Laura ;

Plazinski, Krzysztof ;

Maslinski, WIodzimierz ;

Szwed, Hanna ;

Dabrowski, Rafal .

CYTOKINE, 2015, 74 (01) :164-170

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