High throughput screening of homogenously catalyzed hydrogenations in a continuously perfused membrane reactor

被引：2

作者：

Behr, Arno ^{[1
]}

Halama, Martin ^{[1
]}

Domke, Lutz ^{[1
]}

机构：

[1] Tech Univ Dortmund, Lehrstuhl Tech Chem, Emil Figge Str 66, D-44227 Dortmund, Germany

来源：

CHEMICAL ENGINEERING RESEARCH & DESIGN | 2017年 / 123卷

关键词：

Homogeneous catalysis; Hydrogenation; Membrane reactor; High throughput screening; Reduction; ASYMMETRIC HYDROGENATION; COMBINATORIAL APPROACH; HOMOGENEOUS CATALYSIS; MULTIPHASE REACTIONS; 2-PHASE REACTOR; PRE-SATURATOR; EXPERIMENTATION; SUBSTRATE; LIBRARY; SCALE;

D O I：

10.1016/j.cherd.2017.04.030

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

A new concept of a continuously working membrane reactor was developed and successfully used for hydrogenation screening reactions. Thus, an innovative concept intends the separation of the hydrogen source from the reaction medium. This method guarantees a constant pressure over the reaction time, but allows at the same time a rapid variation of the reaction conditions (reaction time, temperature, pressure of hydrogen), what can be carried out easily. Investigations concerning the choice of membrane material, retention times of each run and phase separation of the sequences were conducted. Using toluene as reaction solvent and propylene carbonate and water as a wash solution, 1-octene, carvone and (-)-beta-pinene were hydrogenated and the results compared to those yielded with a batch reactor. (C) 2017 Institution of Chemical Engineers. Published by Elsevier B.V. All rights reserved.

引用

页码：23 / 34

页数：12

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