Probiotics in Functional Gastrointestinal Disorders

被引：29
作者：
Hojsak, Iva [1 ,2 ,3 ]
机构：
[1] Childrens Hosp Zagreb, Referral Ctr Pediat Gastroenterol & Nutr, Zagreb, Croatia
[2] Univ Zagreb, Sch Med, Zagreb, Croatia
[3] Univ JJ Strossmayer, Sch Med Osijek, Osijek, Croatia
来源：
PROBIOTICS AND CHILD GASTROINTESTINAL HEALTH: ADVANCES IN MICROBIOLOGY, INFECTIOUS DISEASES AND PUBLIC HEALTH, VOL 10 | 2019年 / 1125卷
关键词：
Functional abdominal pain; Infantile colic; Irritable bowel syndrome; Lactobacillus; Probiotics; IRRITABLE-BOWEL-SYNDROME; REUTERI DSM 17938; LACTOBACILLUS-RHAMNOSUS GG; PLACEBO-CONTROLLED TRIAL; DOUBLE-BLIND; ABDOMINAL-PAIN; CHILDHOOD CONSTIPATION; INTESTINAL MICROBIOTA; MOLECULAR ANALYSIS; COLONIC TRANSIT;
D O I：
10.1007/5584_2018_321
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Infantile colic, constipation, functional abdominal pain (FAP), and irritable bowel syndrome (IBS) are the most common functional gastrointestinal disorders (FGID). This chapter will review current evidence on the role of probiotics in the treatment of these FGID. The etiology of FGID is considered multifactorial, but the importance of intestinal microbiota in their development has been repeatedly emphasized. As a consequence, the potential role of probiotics in their treatment is being increasingly scrutinized. Presently, the strongest evidence of efficacy is for the use of Lactobacillus reuteri (L reuteri) DSM 17938 at the dose of 10(8) CFU/day for the treatment of infantile colic in breastfed infants. Limited, yet encouraging, evidence exists for Lactobacillus rhamnosus GG (LGG) at the dose of 3 x 10(9) CFU and for a multi-strain preparation for the treatment of IBS. In the treatment of FAP, there is some evidence for the use of L reuteri DSM 17938 at the dose of at least 10(8) CFU/day.
引用
收藏
页码：121 / 137
页数：17
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