Secondary metabolites from mangrove-associated fungi: source, chemistry and bioactivities

被引：109

作者：

Chen, Senhua ^{[1
,2
]}

Cai, Runlin ^{[1
,3
]}

Liu, Zhaoming ^{[1
,4
]}

Cui, Hui ^{[1
,5
]}

She, Zhigang ^{[1
]}

机构：

[1] Sun Yat Sen Univ, Sch Chem, Guangzhou 510006, Peoples R China

[2] Sun Yat Sen Univ, Sch Marine Sci, Guangzhou 510006, Peoples R China

[3] Shantou Univ, Coll Sci, Shantou 515063, Peoples R China

[4] Guangdong Acad Sci, Guangdong Inst Microbiol, State Key Lab Appl Microbiol Southern China, Guangzhou 510070, Peoples R China

[5] Guangzhou Univ Chinese Med, Sch Pharmaceut Sci, Guangzhou 510006, Peoples R China

来源：

NATURAL PRODUCT REPORTS | 2022年 / 39卷 / 03期

基金：

中国国家自然科学基金;

关键词：

D O I：

10.1039/d1np00041a

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Covering 1989 to 2020 The mangrove forests are a complex ecosystem occurring at tropical and subtropical intertidal estuarine zones and nourish a diverse group of microorganisms including fungi, actinomycetes, bacteria, cyanobacteria, algae, and protozoa. Among the mangrove microbial community, mangrove associated fungi, as the second-largest ecological group of the marine fungi, not only play an essential role in creating and maintaining this biosphere but also represent a rich source of structurally unique and diverse bioactive secondary metabolites, attracting significant attention of organic chemists and pharmacologists. This review summarizes the discovery relating to the source and characteristics of metabolic products isolated from mangrove-associated fungi over the past thirty years (1989-2020). Its emphasis included 1387 new metabolites from 451 papers, focusing on bioactivity and the unique chemical diversity of these natural products.

引用

页码：560 / 595

页数：36