GERMLINE MODIFICATION USING MOUSE SPERMATOGONIAL STEM CELLS

被引：23
作者：
Kanatsu-Shinohara, Mito [1 ]
Shinohara, Takashi [1 ]
机构：
[1] Kyoto Univ, Dept Mol Genet, Grad Sch Med, Kyoto, Japan
来源：
METHODS IN ENZYMOLOGY, VOL 477: GUIDE TO TECHNIQUES IN MOUSE DEVELOPMENT, PART B: MOUSE MOLECULAR GENETICS, SECOND EDITION | 2010年 / 477卷
关键词：
LONG-TERM PROLIFERATION; MEDIATED GENE DELIVERY; KNOCKOUT MICE; IN-VITRO; TRANSPLANTATION; SPERMATOGENESIS; TRANSMISSION; TRANSDUCTION; GENERATION; GROWTH;
D O I：
10.1016/S0076-6879(10)77002-6
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Spermatogonial stem cells (SSCs) in the testes are a new target for germline modification. With the development of an in vitro culture system and spermatogonial transplantation technique, SSCs can now be manipulated and used as an alternative to embryonic stem cells for knockout mice production. The genetic and epigenetic stability of SSCs provide new possibilities for the application of germline mutagenesis in a wide range of animals.
引用
收藏
页码：17 / 36
页数：20
相关论文
共 51 条
[1]   SPERMATOGENESIS FOLLOWING MALE GERM-CELL TRANSPLANTATION [J].
BRINSTER, RL ;
ZIMMERMANN, JW .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (24) :11298-11302
[2]   GERMLINE TRANSMISSION OF DONOR HAPLOTYPE FOLLOWING SPERMATOGONIAL TRANSPLANTATION [J].
BRINSTER, RL ;
AVARBOCK, MR .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (24) :11303-11307
[3]   Rat spermatogenesis in mouse testis [J].
Clouthier, DE ;
Avarbock, MR ;
Maika, SD ;
Hammer, RE ;
Brinster, RL .
NATURE, 1996, 381 (6581) :418-421
[4]   Transplantation of germ cells from glial cell line-derived neurotrophic factor-overexpressing mice to host testes depleted of endogenous spermatogenesis by fractionated irradiation [J].
Creemers, LB ;
Meng, X ;
den Ouden, K ;
van Pelt, AMM ;
Izadyar, F ;
Santoro, M ;
Sariola, H ;
de Rooij, DG .
BIOLOGY OF REPRODUCTION, 2002, 66 (06) :1579-1584
[5]   Pluripotent Stem Cells Derived From Adult Human Testes [J].
Golestaneh, Nady ;
Kokkinaki, Maria ;
Pant, Disha ;
Jiang, Jiji ;
DeStefano, David ;
Fernandez-Bueno, Carlos ;
Rone, Janice D. ;
Haddad, Bassem R. ;
Gallicano, G. Ian ;
Dym, Martin .
STEM CELLS AND DEVELOPMENT, 2009, 18 (08) :1115-1125
[6]   Pluripotency of spermatogonial stem cells from adult mouse testis [J].
Guan, K ;
Nayernia, K ;
Maier, LS ;
Wagner, S ;
Dressel, R ;
Lee, JH ;
Nolte, J ;
Wolf, F ;
Li, MY ;
Engel, W ;
Hasenfuss, G .
NATURE, 2006, 440 (7088) :1199-1203
[7]   Adeno-associated virus (AAV)-mediated transduction of male germ line stem cells results in transgene transmission after germ cell transplantation [J].
Honaramooz, Ali ;
Megee, Susan ;
Zeng, Wenxian ;
Destrempes, Margret M. ;
Overton, Susan A. ;
Luo, Jinping ;
Galantino-Homer, Hannah ;
Modelski, Mark ;
Chen, Fangping ;
Blash, Stephen ;
Melican, David T. ;
Gavin, William G. ;
Ayres, Sandra ;
Yang, Fang ;
Wang, P. Jeremy ;
Echelard, Yann ;
Dobrinski, Ina .
FASEB JOURNAL, 2008, 22 (02) :374-382
[8]   Genetic and epigenetic properties of mouse male germline stem cells during long-term culture [J].
Kanatsu-Shinohara, M ;
Ogonuki, N ;
Iwano, T ;
Lee, J ;
Kazuki, Y ;
Inoue, K ;
Miki, H ;
Takehashi, M ;
Toyokuni, S ;
Shinkai, Y ;
Oshimura, M ;
Ishino, F ;
Ogura, A ;
Shinohara, T .
DEVELOPMENT, 2005, 132 (18) :4155-4163
[9]   Anchorage-independent growth of mouse male germline stem cells in vitro [J].
Kanatsu-Shinohara, M ;
Inoue, K ;
Lee, J ;
Miki, H ;
Ogonuki, N ;
Toyokuni, S ;
Ogura, A ;
Shinohara, T .
BIOLOGY OF REPRODUCTION, 2006, 74 (03) :522-529
[10]   CD9 is a surface marker on mouse and rat male germline stem cells [J].
Kanatsu-Shinohara, M ;
Toyokuni, S ;
Shinohara, T .
BIOLOGY OF REPRODUCTION, 2004, 70 (01) :70-75
123456