Enzymatic resolution of bicyclo[n.1.0]alkan-1-ols derivatives:: Preparation of optically active α-substituted α-methylcycloalkanones.

被引：16

作者：

Morisson, V ^{[1
]}

Barnier, JP ^{[1
]}

Blanco, L ^{[1
]}

机构：

[1] Univ Paris 11, Inst Chim Mol Orsay, Lab Carbocycles, Associe CNRS, F-91405 Orsay, France

来源：

TETRAHEDRON | 1998年 / 54卷 / 27期

关键词：

D O I：

10.1016/S0040-4020(98)00411-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Optically active alpha-methyl alpha-substituted cycloalkanones are prepared by a chemoenzymatic sequence which involves a Lipozyme(R)-catalyzed transesterification of 1-(chloroacetoxy)bicyclo[n.1.0]alkanes and ring opening of these cyclopropanol derivatives. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：7749 / 7764

页数：16

共 24 条

[21] PREPARATION OF OPTICALLY-ACTIVE 1-AMINOALKYLPHOSPHONIC ACIDS BY STEREOSELECTIVE ENZYMATIC-HYDROLYSIS OF RACEMIC N-ACYLATED 1-AMINOALKYLPHOSPHONIC ACIDS
SOLODENKO, VA
KASHEVA, TN
KUKHAR, VP
KOZLOVA, EV
MIRONENKO, DA
SVEDAS, VK
TETRAHEDRON, 1991, 47 (24) : 3989 - 3998
[22] PREPARATION OF OPTICALLY-ACTIVE N-ALKYL-SUBSTITUTED (S)-1,2-PROPANEDIAMINES AND CD STUDIES OF THEIR PALLADIUM(II) COMPLEXES
SUZUKI, M
NISHIDA, Y
INORGANICA CHIMICA ACTA, 1979, 34 (01) : 61 - 65
[23] Preparation of optically active succinic acid derivatives .1. Optical resolution of 2-benzyl-3-(cis-hexahydroisoindolin-2-ylcarbonyl)propionic acid
Yamaguchi, T
Yanagi, T
Hokari, H
Mukaiyama, Y
Kamijo, T
Yamamoto, I
CHEMICAL & PHARMACEUTICAL BULLETIN, 1997, 45 (09) : 1518 - 1520
[24] PREPARATION OF OPTICALLY-ACTIVE AMINES BY A COMBINATION OF GABRIEL SYNTHESIS AND OPTICAL RESOLUTION - X-RAY CRYSTAL-STRUCTURE OF THE ADDUCT BETWEEN (-)-10,10'-DIHYDROXY-9,9'-BIPHENANTHRYL AND N-(1-TERT-BUTYL-2-OXOAZETIDIN-3-YL)PHTHALIMIDE
TODA, F
SODA, S
GOLDBERG, I
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1993, (19): : 2357 - 2361

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