High blood monocyte counts and neopterin levels in children with autistic disorder

被引：107

作者：

Sweeten, TL ^{[1
]}

Posey, DJ ^{[1
]}

McDougle, CJ ^{[1
]}

机构：

[1] Indiana Univ, Sch Med, Dept Psychiat, Indianapolis, IN 46202 USA

来源：

AMERICAN JOURNAL OF PSYCHIATRY | 2003年 / 160卷 / 09期

关键词：

D O I：

10.1176/appi.ajp.160.9.1691

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Objective: Leukocyte counts and plasma neopterin levels were determined in autistic children and matched healthy comparison subjects. Method: Blood from 31 autistic children and 28 age- and gender-matched healthy comparison subjects was analyzed for numbers of neutrophils, eosinophils, basophils, lymphocytes, monocytes, and total leukocytes and for plasma neopterin levels. Results: The monocyte count and neopterin level were significantly higher in the autistic children than in the comparison subjects. Conclusions: These results suggest that the immune system may be activated in some children with autism.

引用

页码：1691 / 1693

页数：3

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