Nicotine Addiction

被引：1047
作者：
Benowitz, Neal L. [1 ,2 ,3 ]
机构：
[1] San Francisco Gen Hosp, Med Ctr, Med Serv, Div Clin Pharmacol & Expt Therapeut, San Francisco, CA 94110 USA
[2] Univ Calif San Francisco, Dept Med, San Francisco, CA 94143 USA
[3] Univ Calif San Francisco, Dept Bioengn & Therapeut Sci, San Francisco, CA 94143 USA
来源：
NEW ENGLAND JOURNAL OF MEDICINE | 2010年 / 362卷 / 24期
关键词：
GENOME-WIDE ASSOCIATION; BRAIN REWARD SYSTEMS; CIGARETTE-SMOKING; ACETYLCHOLINE-RECEPTOR; LUNG-CANCER; PSYCHIATRIC-DISORDERS; SUSCEPTIBILITY LOCUS; TOBACCO WITHDRAWAL; MONOAMINE-OXIDASE; SEX-DIFFERENCES;
D O I：
10.1056/NEJMra0809890
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
This review gives an account of the cigarette as a highly efficient nicotine delivery system. It explains how nicotine induces pleasure, reduces stress and anxiety, and causes addiction to tobacco smoking. The basis of nicotine addiction rests on its effects on the brain, but addiction is also influenced by learned or conditioned factors, genetics, and social and environmental conditions. Copyright © 2010 Massachusetts Medical Society. All rights reserved.
引用
收藏
页码：2295 / 2303
页数：9
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