Should obese women's access to assisted fertility treatment be limited? A scientific and ethical analysis

被引:23
作者
Tremellen, Kelton [1 ]
Wilkinson, Dominic [2 ,3 ]
Savulescu, Julian [2 ]
机构
[1] Flinders Univ S Australia, Dept Obstet Gynaecol & Reprod Med, Sturt Rd, Adelaide, SA 5042, Australia
[2] Univ Oxford, Fac Philosophy, Oxford Uehiro Ctr Pract Eth, Oxford, England
[3] John Radcliffe Hosp, Dept Neonatol, Oxford, England
基金
英国惠康基金;
关键词
access to treatment; assisted reproduction; ethics; IVF; obesity; BODY-MASS INDEX; WEIGHT-LOSS; PREGNANCY OUTCOMES; RISK; COMPLICATIONS; CONCEPTION; HEALTH;
D O I
10.1111/ajo.12600
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Obesity is associated with a reduction in fertility treatment success and increased risks to mother and child. Therefore guidelines of the Royal Australian and New Zealand College of Obstetricians and Gynaecologists (RANZCOG) suggest that a body mass index exceeding 35kg/m(2) should be an absolute contraindication to assisted fertility treatment such as in vitro fertilisation IVF. In this paper we challenge the ethical and scientific basis for such a ban. Livebirth rates for severely obese women are reduced by up to 30%, but this result is still far better than that observed for many older women who are allowed access to IVF. This prohibition is particularly unjust when IVF is the only treatment capable of producing a pregnancy, such as bilateral tubal blockage or severe male factor infertility. Furthermore, the absolute magnitude of risks to mother or child is relatively small, and while a woman has a right to be educated about these risks, she alone should be allowed to make a decision on proceeding with treatment. We do not prohibit adults from engaging in dangerous sports, nor do we force parents to vaccinate their children, despite the risks. Similarly, we should not prohibit obese women from becoming parents because of increased risk to themselves or their child. Finally, prohibiting obese women's access to IVF to prevent potential harms such as fetal programing' is questionable, especially when compared to that child never being born at all. As such, we believe the RANZCOG ban on severely obese women's access to assisted reproductive treatment is unwarranted and should be revised.
引用
收藏
页码:569 / 574
页数:6
相关论文
共 29 条
  • [1] Australian Bureau of Statistics, 2011, PROF OF HLTH
  • [2] Metabolically Healthy Obesity-Does it Exist?
    Boonchaya-Anant, Patchaya
    Apovian, Caroline M.
    [J]. CURRENT ATHEROSCLEROSIS REPORTS, 2014, 16 (10)
  • [3] The Relation Between Body Mass Index, Mental Health, and Functional Disability: A European Population Perspective
    Bruffaerts, Ronny
    Demyttenaere, Koen
    Vilagut, Gemma
    Martinez, Montserat
    Bonnewyn, Anke
    De Graaf, Ron
    Haro, Josep Maria
    Bernert, Sebastian
    Angermeyer, Matthias C.
    Brugha, Traolach
    Roick, Christine
    Alonso, Jordi
    [J]. CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE, 2008, 53 (10): : 679 - 687
  • [4] Body mass index and short-term weight change in relation to treatment outcomes in women undergoing assisted reproduction
    Chavarro, Jorge E.
    Ehrlich, Shelley
    Colaci, Daniela S.
    Wright, Diane L.
    Toth, Thomas L.
    Petrozza, John C.
    Hauser, Russ
    [J]. FERTILITY AND STERILITY, 2012, 98 (01) : 109 - 116
  • [5] Diabetes mellitus and birth defects
    Correa, Adolfo
    Gilboa, Suzanne M.
    Besser, Lilah M.
    Botto, Lorenzo D.
    Moore, Cynthia A.
    Hobbs, Charlotte A.
    Cleves, Mario A.
    Riehle-Colarusso, Tiffany J.
    Waller, Kim
    Reece, E. Albert
    [J]. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2008, 199 (03) : 237.e1 - 237.e9
  • [6] Lifestyle-related factors and access to medically assisted reproduction†
    Dondorp, W.
    de Wert, G.
    Pennings, G.
    Shenfield, F.
    Devroey, P.
    Tarlatzis, B.
    Barri, P.
    [J]. HUMAN REPRODUCTION, 2010, 25 (03) : 578 - 583
  • [7] Rate of Weight Loss Can Be Predicted by Patient Characteristics and Intervention Strategies
    Finkler, Elissa
    Heymsfield, Steven B.
    St-Onge, Marie-Pierre
    [J]. JOURNAL OF THE ACADEMY OF NUTRITION AND DIETETICS, 2012, 112 (01) : 75 - 80
  • [8] Prioritising for fertility treatments - the effect of excluding women with a high body mass index
    Gillett, W. R.
    Putt, T.
    Farquhar, C. M.
    [J]. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 2006, 113 (10) : 1218 - 1221
  • [9] Patient Selection and Surgical Management of High-Risk Patients with Morbid Obesity
    Guerron, A. Daniel
    Portenier, Dana D.
    [J]. SURGICAL CLINICS OF NORTH AMERICA, 2016, 96 (04) : 743 - +
  • [10] Perceived Discrimination and Stigmatisation against Severely Obese Women: Age and Weight Loss Make a Difference
    Hayden, Melissa J.
    Dixon, Maureen E.
    Dixon, John B.
    Playfair, Julie
    O'Brien, Paul E.
    [J]. OBESITY FACTS, 2010, 3 (01) : 7 - 14